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Estrogen: How it is made and how we get rid of it

Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.

Maca Root: Research-backed Benefits and How It Works

Explore the benefits of Maca root, a cruciferous vegetable with adaptogenic properties, known for balancing hormone levels and aiding menopausal symptoms. Learn about its potential side effects, gene interactions, and the science behind its unique bioactive compounds.

HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions

Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.

Estrogen, histamine, and mast cell connections

Mast cells can be more easily triggered in the presence of high estrogen or estrogen-mimicking compounds. Histamine can also trigger mast cell degranulation. Together, this can cause a lot of symptoms related to mast cell activation.

Thyroid Hormone Levels and Your Genes

The thyroid is a master regulator controlling many of your body’s systems. It is integral for metabolism and body temperature. Learn more about specific thyroid-related variants and check your genetic raw data.

woman with pregnancy test in hand

Genetic links to infertility for women

Your genes may be playing a role in your infertility — and knowing which genetic variants you carry may help you figure out solutions to try.

Low testosterone and your genes

While diet and lifestyle play a role in testosterone levels, in males, there is a strong genetic component as well. Check out your genes to see if they are playing a role in your low T levels — and then check out the Lifehacks.

Fibroids: Genes, root causes, and solutions

Uterine fibroids are a problem for a lot of women, especially after age 30. Fibroids are benign tumors that grow in the muscle cells of the uterus. This article will dig into the causes of fibroids, explain how your genetic variants can add to the susceptibility, and offer solutions that are backed by research. (Member’s article)

Acne: Root Causes & Personal Solutions

Acne is thought to be 80% heritable. Learn how your genetic variants increase your risk of acne and find specific solutions that work for those genetic pathways.

PMS, Genetics, and Solutions

A lot of women know the moodiness and brain fog that comes with premenstrual syndrome (PMS). Studies estimate that PMS is up to 95% heritable – which means that it has a huge genetic component. Learn about the genes and find out which solutions may actually work for you.

Hormones Topic Summary

Utilize our Hormones Topic Summary Reports with your 23andMe or AncestryDNA genetic data to see which articles may be most relevant to you. These summaries are attempting to distill the complex information down into just a few words. Please see the linked articles for details and complete references. (Member’s article)

DHEA and weight

DHEA and Your Weight

DHEA is a hormone that does a lot in the body – including influencing muscle mass and weight. This quick article examines just one aspect of DHEA: how it affects our weight. But the genetic variants included here also impact other impacts of DHEA in the body.