Hemochromatosis Report

  • Highlights in yellow indicate that you have one of the risk variants (heterozygous).
  • Highlights in red indicate that you have two of the risk variants (homozygous).
Gene SNP Risk allele* Your geneotype Meaning
HFE C282Y rs1800562 A
  • AA: hereditary hemochromatosis is possible
  • AG: increased ferritin
  • GG: normal
HFE H63D rs1799945 G
  • GG: possibility of hemochromatosis (mild)
  • CG: pos. increased ferritin
  • CC: normal
HFE S65C rs1800730 T
  • TT: Possible (milder) hemochromatosis
  • AT: pos. increased ferritin
  • AA: normal

 

Hereditary hemochromatosis is a genetic disorder of abnormal iron metabolism. Those who carry the risk alleles for it could absorb too much iron from their diet, which leads to iron overload. The excess iron can be stored in glands and organs, such as heart, liver, pituitary, thyroid, pancreas, joints, and bone marrow, leading to dysfunction.

The Iron Disorders Institute has a lot of information about the symptoms of iron overload.

Actions to Take

Get your iron and ferritin levels checked. Talk to you doctor about the tests needed, or order them yourself through an online lab test site, such as Walk In Lab.

Simply put, the solution is to give blood – whether through a local blood bank, a Red Cross Blood Drive, or through phlebotomy at your doctor’s office.

Read more about hemochromatosis here: Building Up Iron, Genetics, Diet, and Health Effects

Because I know how expensive it can be to chase down the root cause for health issues, these reports are offered on a ‘Pay what you can’ basis. Suggested payment: $5.



Disclaimer: Information given on Genetic Lifehacks is for educational purposes only. Errors are possible, and 23andMe does not guarantee the accuracy of using their data for health purposes.