Histamine intolerance and the methylation cycle

Histamine Intolerance - The genes and pathways of breaking down histamine.

Are you itching by the end of the day?  Miserable in the evening due to heartburn?  Nose constantly stuffy and drippy? Plagued by migraines? All of these (and more) can be related to histamine intolerance. First, symptoms of histamine issues can be more than just watery eyes and sneezing when the pollen count rises each spring. From …

Lactose Intolerance: The genetics of not producing lactase

Lactose1

Lactose, a sugar in milk, is broken down by the enzyme lactase.  For some people, the production of the lactase enzyme is decreased when they become an adult; this decrease is driven by a genetic variation near the LCT gene.  This means that some adults are genetically predisposed to not be able to consume larger …

Genetics of Cholesterol Levels

cholesterol-genes

Heart disease is the leading cause of death in the US and around the world, and hand-in-hand with heart disease goes the often demonized cholesterol.  Standard medical advice on ideal cholesterol levels and cardiovascular disease are often confusing, ever changing, and downright contradictory.  So here is a look at some of the ways our genes are …

How Well Does YOUR Body Convert Beta-Carotene to Vitamin A?

How Well Do YOU ConvertBeta-Carotene to Vitamin A-

Everyone knows that carrots and sweet potatoes are great sources of vitamin A, right?  Turns out it isn’t that straightforward for everyone.  The beta-carotene in orange fruits and vegetables has to be converted into the form of vitamin A that our bodies can use, and genetics plays a huge role in how well we do …

The Link Between Vitamin D, MS, and Your Genes

Many have drawn the conclusion that there must be a link between Vitamin D and multiple sclerosis based on the distribution of cases at certain latitudes.  [link] A study in 2009 titled “Expression of the Multiple Sclerosis-Associated MHC Class II Allele HLA-DRB1*1501 Is Regulated by Vitamin D” discusses the connection between MS and Vitamin D. …

COMT: Genetic Influence on Heart Disease and Interaction with Aspirin, Vitamin E

COMT (2)

Everyone knows that aspirin protects against heart disease, right? Well, it turns out that is only true for some of us, and for others it can actually slightly increase the risk of heart disease.  It all depends on a COMT polymorphism. Catechol-O-methyltransferase (COMT) is the gene that codes for an enzyme that breaks down dopamine, …

Vitamin D Levels and Genetic Variations

Vitamin D Levels and Your Genes

Vitamin D, the vitamin that is not really a vitamin… A prohormone that is synthesized in the skin using cholesterol in a chemical reaction with UVB radiation from the sun, vitamin D is essential to many processes in the body. Vitamins are defined as substances that are necessary to obtain from the diet; vitamin D doesn’t meet …