Histamine, Mast Cell Activation, and Early Morning Insomnia
Histamine rising in the early morning hours may cause early waking insomnia. Mast cells and circadian rhythm disruption at the root.
Histamine rising in the early morning hours may cause early waking insomnia. Mast cells and circadian rhythm disruption at the root.
Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance.
Genetics plays a role in how well your body breaks down histamine. Histamine that is out of balance with the body’s ability to break it down can cause symptoms that are collectively known as histamine intolerance. Discover how to check your genes that are involved with histamine levels.
Drinking alcohol is often a problem for people with histamine intolerance. Learn about the pathways that are involved and how to avoid alcohol-induced reactions.
Mast cells can be more easily triggered in the presence of high estrogen or estrogen-mimicking compounds. Histamine can also trigger mast cell degranulation. Together, this can cause a lot of symptoms related to mast cell activation.
Do you know of someone with unexplained heart palpitations, spiking blood pressure, dizziness, and tinnitus? Discover how research is linking these symptoms to histamine, mast cells, and the spike protein.
Interested in low histamine foods and recipes? This article focuses on foods high in histamine so you can easily eliminate them from your diet.
It can be difficult sometimes to come up with new breakfast ideas for a low histamine diet. Here is a recipe for a low histamine smoothie bowl for a quick breakfast. (Member’s article)
Histamine plays several important roles in the body. Learn more about the newest research into histamine intolerance and mast cells.
On a low histamine diet and craving salsa and tortilla chips? Here is a quick recipe for a low histamine salsa using roasted red peppers instead of tomatoes.
Looking for low histamine treats? Here is a mint shake recipe low in histamines, and an excellent source of luteolin, a mast cell stabilizer.
Study: MWF of the corpus callosum is a robust measure of remyelination: Results from the ReBUILD trial Published: PNAS, May 2023 Overview: The study included 50 multiple sclerosis (MS patients) and looked at the brain regions that are rich in myelin. In MS, the body attacks the myelin sheath. The study looked at ways to assess the therapeutic effect of compounds on the remyelination of neurons through imaging. While important for researchers to know the best MRI imaging biomarkers, what I found interesting is the effect on myelin from a first-generation anti-histamine, clemastine. MRI scans were done at baseline, 3 months and 5 months. Half of the patients received clematine and the other half a placebo from months 3 to 5. The results showed that clemastine stimulated the differentiation of stem cells that make myelin. This isn’t the first study on clemastine showing positive results for people with MS. However, it is important in that it shows how and where the remyelination is taking place. Clemastine used to be available OTC in the US as Dayhist Allergy and … Read more
New research suggests the benefits of luteolin (a flavonoid found in fruits, vegetables, and herbs) may include anti-inflammatory and neuroprotective properties.
The MTHFD1 gene encodes an enzyme in the folate cycle. Genetic variants here can indicate a greater need for choline or folate in the diet.
Phthalates are a type of chemical used as plasticizers to make plastics more pliable. There has been a lot of research on the endocrine-disrupting effects of phthalates. Your genetic variants may impact whether phthalates are a problem for you.
Alpha-gal syndrome causes allergic reactions to meat (beef, pork, lamb) after being bitten by a tick. Find out why and which genetic pathways are involved.
Discover the complex interplay of genetics and environment in ADHD susceptibility. Learn how circadian rhythm and neurotransmitter genes contribute to the disorder, and how toxicant exposure may increase risk.
Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.
Atrial fibrillation is an irregular heartbeat in the atrium. Genetic variants combine with inflammation and environmental triggers in causing A-fib.
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.