Mast cells: MCAS, genetics, and solutions

Mast Cell Activation Syndrome, or MCAS, is a recently recognized disease involving mast cells that are misbehaving in various ways.  Symptoms of MCAS can include  abdominal pain, nausea, itching, flushing, hives, headaches, heart palpitations, anxiety, brain fog, and anaphylaxis. This article explains how mast…

HLA-B27: Genetic Variants That Increase Susceptibility to Autoimmune Diseases

HLA-B27 - check your 23andMe or AncestryDNA

Our immune system does an awesome job (most of the time) of fighting off pathogenic bacteria and viruses. But to fight off these pathogens, the body needs to know that they are the bad guys. This is where the HLA system comes in. This article…

Quercetin: Scientific studies + genetic connections

Quercetin is a natural flavonoid that acts both as an antioxidant and anti-inflammatory. This potent flavonoid is found in low levels in many fruits and vegetables, including elderberry, apples, and onions. As a supplement, quercetin has many positive health benefits. This article focuses on…

Familial Mediterranean Fever: Often misdiagnosed!

Familial Mediterranean fever (FMF) is a genetic condition of inflammatory episodes that cause painful joints, pain in the abdomen, or pain in the chest, and is most often accompanied by a fever. This condition often shows up first in childhood with unexplained fever and…