Should you eat organic? Genes that influence pyrethroid metabolism.

Is buying organic worth the extra cost? There isn’t a one-size-fits-all answer to that question. Pesticides that are sprayed on conventionally grown foods affect people differently. Some people carry genetic variants that decrease their ability to detoxify specific pesticides, others may be more resilient….

Should you eat organic? Detoxifying Organophosphates

Is buying organic worth the extra cost? There isn’t a one-size-fits-all answer to that question. Pesticides that are sprayed on conventionally grown foods affect people differently. Some people carry genetic variants that decrease their ability to detoxify specific pesticides, others may be more resilient….

BPA: How Your Genes Influence BPA Detoxification

BPA, a chemical found in some plastics, has been linked to a variety of effects on people including obesity, insulin resistance, and epigenetic effects on the fetus.  It is everywhere in our food supply. In fact, a CDC report showed that 92% of people…

CYP3A4 and CYP3A5: How genes impact prescription medications

Our bodies break down (metabolize) drugs and other toxins through a group of enzymes known as the CYP450 family. Different CYP enzymes break down different substances, and we all carry genetic variants that can impact whether we metabolize a drug quickly or slowly. The…

CYP2C19 – Metabolizing medications

The CYP2C19 enzyme is responsible for the breakdown of several popular drugs including proton pump inhibitors (Prilosec, Nexium, Prevacid), certain anti-epileptics, and an antiplatelet drug (Plavix).  CYP2C19 is also involved in activating and breaking down some hormones such as progesterone. There are variants of…

Liver Detox Genes: CYP2C9 Genotypes and Drug Metabolism

Have you ever wondered why certain medications don’t work well for you? Genetic variants can change how fast or how slow the medication is broken down in your body. CYP2C9 is a gene that codes for an enzyme that metabolizes quite a few medications…

Gulf War Illness: Genetic susceptibility and current research

A question from a patron via Patreon prompted me to look into the link between genes and Gulf War Illness. I wanted to share what I found in case it can help other veterans who are dealing with the aftereffects of their service to…

Is the nootropic drug modafinil likely to work for you?

modafinil genes

Modafinil is being used as a nootropic drug that increases alertness and gives a sense of well being — to some users. Like most drugs, individual results seem to vary.  One reason for the variation is a common genetic variation in the COMT gene….

Why Allegra may not work as well for you: genetics of ABCB1 proteins (Patrons only)

Ever wonder why a certain medication may work great for a friend and do nothing for you?  One reason could be your genes. Let’s take fexofenadine (Allegra) for example.  You have watery eyes and a drippy nose during spring allergy season and pop an…

Detoxifying Phthalates:  Genes and Diet

There have been several recent studies about phthalates that have piqued my interest. I decided it was time to look into the science behind the stories and see if there really is anything to the scare-tactic type headlines about phthalates. Below are my notes…