Pyruvate Dehydrogenase Deficiency – Mitochondrial dysfunction

What is Pyruvate dehydrogenase? Pyruvate dehydrogenase is involved in the production of cellular energy in the mitochondria.  It acts as a catalyst in the conversion of pyruvate into acetyl-CoA, which is used in the citric acid cycle (Kreb’s cycle) in cellular respiration and production…

Medium chain acyl-CoA dehydrogenase deficiency

Does your blood sugar crash when you don’t eat for a day? Do you find that coconut oil in your coffee doesn’t work well for you? It could be that your body has trouble using medium-chain fatty acids for energy. What is medium-chain acyl-CoA…

Short-chain Acyl-CoA Dehydrogenase Deficiency

Have you tried fasting or a perhaps a ketogenic diet and felt horrible?  If so, one reason could be found in the way that your body uses different types of fats. Using Fat for Fuel: Short-chain fatty acids The human body is wonderfully made…