Increased Inflammation and IL-17A Genetic Variants

Articles about ‘inflammation’ seem to be everywhere these days, and inflammation seems to be blamed for everything from heart disease to mood disorders to obesity. But how does this somewhat nebulous idea of too much inflammation tie into our genes?  It seems that some…

Color TV has made us fat: melatonin, genetics, and light at night

Color TV has made us fat! Nope, not just because of the commercials advertising Taco Bell at night nor the fact that we are laying on our couches watching those commercials.  The flickering blue light that can be seen each evening pouring out of…

Should you vaccinate your kids if they have the MTHFR mutation?

I recently read (for the millionth time) that anyone who carries MTHFR variants should not be vaccinated.  The reason given is that those with decreased MTHFR enzyme activity cannot detoxify or ‘handle’ vaccinations, often with references to mercury in the vaccines. This article reviews…

Genetic Variants that Cause G6PD Deficiency

What is the G6PD gene? The G6PD gene codes for the glucose-6-phosphate dehydrogenase enzyme. The G6PD enzyme is part of the pentose phosphate pathway and supplies the energy needed to produce NADPH. NADPH then is responsible for maintaining the supply of glutathione, an antioxidant.  Red…

Detoxifying Phthalates:  Genes and Diet

There have been several recent studies about phthalates that have piqued my interest. I decided it was time to look into the science behind the stories and see if there really is anything to the scare-tactic type headlines about phthalates. Below are my notes…

Saturated Fat and Your Genes

There has been a decades-long debate about which type of fat is best: saturated fat or polyunsaturated fat. Those in the paleo and ketogenic world are quick to tout the benefits of saturated fat; the American Heart Association promotes polyunsaturated fats[ref]. And most people…

Carbohydrate metabolism: Your genes play a role in insulin and blood glucose levels

Sometimes the things that everyone seems to accept as gospel don’t always hold true when researchers actually look into them, especially in regards to nutrition. Take the glycemic index for example: Around since the 1980’s, accepted dogma holds that white bread will very quickly…

Interaction between high fat diet, blood pressure, and your genes

Wondering if you should cut down on red meat and fat to lower your blood pressure? According to a new study, it could depend on your genes. A recent study in the Journal of the American Heart Association illustrates once again the interaction between…

Diet – Gene Interaction in Type 2 Diabetes Risk

A new study just came out in the FASEB Journal that looked at the interaction between polyunsaturated fat and the Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-α (PPARGC1A) gene.  The study found that those with the minor allele (C) of rs4235308 combined with a lower PUFA (polyunsaturated…

Building Up Iron: Check your genes to see how iron affects your health

Hemochromatosis is a fairly common genetic disease that causes iron to build up in the body. Knowing that you carry the genetic variants for hemochromatosis can literally add years to your life since you can prevent the buildup of iron through giving blood. This…