Aspirin, colon cancer, and genetics

I don’t usually blog about cancer risks, mainly because I don’t want to alarm anyone unnecessarily. There are lots of very common genetic variants that add just a little bit to your risk for cancer, but the bigger picture for most cancers seems to…

Genetics and Mannose-Binding Lectin

Mannose-binding lectin, also known as mannose-binding protein, is involved in the body’s innate defense against infection. Lectin is a general term for a protein that binds to a carbohydrate.  (A lot of what you read about lectins on alternative health blogs is referring to…

Ancestral Diet: Omega-3 and Omega-6 Fatty Acids

Butter will give you a heart attack! Only cook with Crisco  vegetable oil  canola oil   olive oil.  Wait — everyone is switching back to saturated fats. Olive oil, grapeseed oil, avocado oil,  — cold expeller pressed, extra virgin hand squeezed oil from pine nuts grown in…

Liver Detox Gene – CYP17A1

This is part of a continuing series on the Phase I and Phase II detoxification system. CYP17A1 is involved in the formation and metabolism of steroid hormones such as precursors to androgens and estrogens.  Major pathological disorders involved with this gene include adrenal hyperplasia….

Genes linked to susceptibility to lupus

Systemic lupus erythematosus, more commonly referred to as lupus, is a complex autoimmune disease that can affect many different organs of the body.  Some of the more common symptoms include fatigue, joint pain, a butterfly-shaped rash on the face, photosensitivity, headaches, and more.   It is…

Inflammatory Bowel, Crohn’s Disease, and Gut Microbes

“Fix your gut!” seems to be the standard advice from most healthy living blogs, but concrete advice on how to actually accomplish this seems to be lacking. While general suggestions abound, specific actions that actually work for an individual are hard to find. I…

Mono and genetics

Ever wonder why some people get mono and others don’t?  Almost 95% of adults carry antibodies to the Epstein Barr virus that causes mono, but less than 30% of people are estimated to get mono.  [CDC.gov]   Turns out that there may be a genetic susceptibility…

Diabetes and your genes – TCF7L2 snp

See my previous article on Type 2 Diabetes for other SNPs associated with the condition. A new study came out this week on a genetic polymorphism and its association with diabetes.  I think it is important if you have type 2 diabetes, or if it runs…

SOD1: Genetic Variants in Our Antioxidant Defense System

Superoxide dismutase 1 (SOD1) is the gene that codes for the copper-zinc superoxide dismutase enzymes which help protect against oxidative stress and detoxify reactive oxygen species. Three types of superoxide dismutases are part of our built-in antioxidant system:  SOD1, found in the cytosol or…

How to check your genetic data for celiac genes

Celiac disease is an autoimmune disorder in which gluten causes damage to the villi in the small intestines. Gluten is a protein found in wheat, barley, rye, and spelt. When people with celiac consume even very small amounts of gluten their body mounts a…