Phase 2 Detoxification – UGTs

This is part of an ongoing series on the genes involved in detoxification. UDP-glucuronosyltransferase (abbreviated UGT) creates a glucuronidation reaction, which is a big part of phase II detoxification.  Once a drug, toxin, or other substance is broken down in a phase I reaction…

Liver Detox Genes – CYP2A6

This is part of an ongoing series on the genes involved in Phase I detoxification. The CYP2A6 enzyme is involved in the metabolism of nicotine, several cancer drugs,  valproic acid, and coumarin. (Full list of drugs on Wikipedia). The hormone estradiol is an inducer of…

Liver Detox Genes – Cytochrome P450

This is the first in what will (hopefully!) be a good series of posts on genetics, liver function, and detoxification. In reading natural health blogs, the buzzwords these days always seem to include ‘detox’ and ‘cleanse’.  There is a lot of general talk about…

Low Histamine Mint Shake

Not only is this shake low in histamines, but it is an excellent source of luteolin, a mast cell stabilizer.  So for anyone wanting a delicious, summery desert option, grab your blender and some ice cream.   I added some pea shoots for an…

Hemochromatosis – Genes involved

Hemochromatosis is a fairly common genetic disease that causes iron to build up in the body. Knowing that you carry the genetic variants for hemochromatosis can literally add years to your life since you can prevent the buildup of iron through giving blood. This…

Alzheimer’s and APOE genotype

One very important gene that has been very well researched for Alzheimer’s disease is the APOE gene. This gene is involved in carrying cholesterol and other fats in your bloodstream, and a common variant of the gene is linked to a higher risk of…

Are you a non-secretor of your blood type?

FUT2 non-secretor 23andMe

Your genes control the species of bacteria that live in your gut microbiome. And your gut microbiome can help defend against — or make you vulnerable to — chronic diseases. A genetic variant in the FUT2 gene controls whether or not you secrete your…