Genetics and Gum Disease

I read a study last week that piqued my interest in the interplay between genetics and gum disease.  Maybe there is a genetic reason for my tendency towards bleeding gums when the hygienist stabs her probe into them?  I was intrigued to look into…

Genes linked to susceptibility to lupus

Systemic lupus erythematosus, more commonly referred to as lupus, is a complex autoimmune disease that can affect many different organs of the body.  Some of the more common symptoms include fatigue, joint pain, a butterfly-shaped rash on the face, photosensitivity, headaches, and more.   It is…

Inflammatory Bowel, Crohn’s Disease, and Gut Microbes

“Fix your gut!” seems to be the standard advice from most healthy living blogs, but concrete advice on how to actually accomplish this seems to be lacking. While general suggestions abound, specific actions that actually work for an individual are hard to find. I…

Mono and genetics

Ever wonder why some people get mono and others don’t?  Almost 95% of adults carry antibodies to the Epstein Barr virus that causes mono, but less than 30% of people are estimated to get mono.  [CDC.gov]   Turns out that there may be a genetic susceptibility…

Diabetes and your genes – TCF7L2 snp

See my previous article on Type 2 Diabetes for other SNPs associated with the condition. A new study came out this week on a genetic polymorphism and its association with diabetes.  I think it is important if you have type 2 diabetes, or if it runs…

SOD1: Genetic Variants in Our Antioxidant Defense System

Superoxide dismutase 1 (SOD1) is the gene that codes for the copper-zinc superoxide dismutase enzymes which help protect against oxidative stress and detoxify reactive oxygen species. Three types of superoxide dismutases are part of our built-in antioxidant system:  SOD1, found in the cytosol or…

How to check your genetic data for celiac genes

One of my main reasons for doing 23andMe testing was to figure out if I was genetically susceptible to celiac disease.  I went gluten-free about five years ago and have felt so much better that I didn’t want to go back to eating gluten…

Adiponectin levels, glucose regulation, and your genes

Adiponectin, a hormone secreted from adipose (fat) tissue, is involved in glucose regulation.  Studies show that low levels of adiponectin correlate with insulin resistance and diabetes.  Interestingly, although adiponectin is secreted from adipose tissue, levels of the hormone are generally lower in obese individuals….

Osteoporosis Genes

Osteoporosis is a degenerative bone disease facing many of us as we age. Affecting about 54 million people in the US currently, this is a disease that is estimated to affect 50% of women and 25% of men in their lifetime. While perhaps not…

Type II Diabetes – Genetic Connections

According to the American Diabetes Association, 9.3% of the US population has diabetes (2012 numbers).  Diabetes was the 7th leading cause of death in the US in 2010.  The genes involved in increasing risk for type-2 diabetes  indicate some of the variations in causes:…