UCP2 Gene: Weight Loss Lifehacks

Turning up the heat on your metabolism is the job for UCP2. The UCP2 gene codes for an uncoupling protein that works in the mitochondria (energy powerhouse) of our cells, producing heat through the uncoupling of the protons. It is found in a variety…

Weight Loss Genetics – MC4R Revisited

I was catching up on podcasts this weekend and listened to a fascinating one by Dr. Rhonda Patrick.  She does the Found My Fitness podcast and had recently interviewed Dr. Panda.  The interview was on circadian rhythms and time restricted feeding.  In a nutshell, time…

Weight loss genetics – GNB3 C825T

I’m geeking out this week and diving deep into the genetics of weight and obesity. One fairly well-studied variant, rs5443, confers a 2x to 3x risk of obesity and is found in the GNB3 gene. So what is the GNB3 gene?  The G protein β-polypeptide…

Weight Loss Genetics – Obesity Virus?

When looking at the obesity epidemic around the world, one thing becomes clear: it is complicated!  For years we have been told to eat less and exercise more.  And while that is good, healthy advice, it doesn’t seem to be curing the epidemic.  According to…

Weight Loss Genetics – Ghrelin

This is the beginning of a series of articles looking at the genetic SNPs involved in weight loss. One of the first things to come to mind when wanting to lose weight is controlling appetite.  Everyone who has been on a diet understands the…

Adiponectin levels, glucose regulation, and your genes

Adiponectin, a hormone secreted from adipose (fat) tissue, is involved in glucose regulation.  Studies show that low levels of adiponectin correlate with insulin resistance and diabetes.  Interestingly, although adiponectin is secreted from adipose tissue, levels of the hormone are generally lower in obese individuals….