Your genes interact with the foods you eat to shape your health!
Knowing which specific nutrients you may ‘genetically’ need more of can be the key to both solving health issues and optimizing wellness.
This section includes information on:
Vitamins & Your Genes
The SIRTfoods diet is gaining popularity once again due to the endorsement from a few popular celebrities. The diet plan is based on the 2016 book The SIRTfood Diet, which proposes weight loss occurs by activating sirtuins. Find out what exactly a sirtuin does, the genetic variants in the SIRT genes, and whether this weight loss concept stands up to the research.
Like most nutrients, our genes play a role in how vitamin C is absorbed, transported, and used by the body. This can influence your risk for certain diseases, and it can make a difference in the minimum amount of vitamin C you need to consume each day.
Vitamin B6 is an important co-factor in hundreds of different enzymatic reactions. Low levels of B6 are linked to an increased risk of diabetes, cardiovascular disease, neurodegenerative diseases, and cancer. B6 is also important for reducing oxidative stress and inflammation.
Biotin, also known as vitamin B7 or vitamin H, is a cofactor which aids in the metabolism of fats, carbohydrates, and proteins. Biotin deficiency due to diet is pretty rare, but there are genetic variants that can increase your risk for biotin deficiency or insufficiency.
Genetics plays a huge role in how well you convert the carotenes into retinol. Some people are great at converting beta-carotene in their diet into the retinol form. Others carry genetic variants that significantly impair that conversion.
There are several genes that can influence your absorption, transport, and need for vitamin B12. Some people need higher amounts of B12, and some people thrive on different forms of B12. Take a look at your genetic data to see if you should up your intake of B12. (Member's article)
Food Sensitivities & Genetics
Genetic variants of the BChE gene decrease this enzyme’s activity. This can lead to various and seemingly unconnected consequences… such as an increased risk for Parkinson’s or a food sensitivity to nightshade vegetables such as potatoes, tomatoes, and eggplant.
Our ancient ancestors lived much differently than we do today. They were hunter-gatherers, living off of fish, meat, and plant foods that they gathered. A huge shift took place when those hunter-gatherers began farming, growing grains and storing them so that there would be food available all year. Learn if you carry the hunter- gatherer or farmer gene variant.
Chronic headaches, sinus drainage, itchy hives, problems staying asleep, and heartburn -- all of these symptoms can be caused by the body not breaking down histamine very well. Your genetic variants could be causing you to be more sensitive to foods high in histamine. Check your genetic data to see if this could be at the root of your symptoms.
Mushrooms contain a healthy antioxidant called ergothioneine. But for people with a OCTN1 genetic variant, this antioxidant can be too much of a good thing, leading to intestinal problems. Check your genetic data to see if you carry this mushroom intolerance variant.
Whether or not you produce the dairy digesting enzyme lactase as an adult is dependent on a common genetic variant. Discover whether you are genetically lactose intolerant - and how to hack this with the right probiotics.
Studies show some great benefits for disease prevention and cognitive function in people who drink coffee. But your genes make a difference in both whether you will benefit from coffee and how your body reacts to caffeine. Check your genes and decide how you much coffee you should be drinking. (Member's article)
For some people, stacking caffeine with carbohydrates will raise their blood glucose levels more than just carbs alone. Learn whether you carry this genetic combo and what to do about it. (Member's article)
We all vary in how well we convert the plant-based omega-3 oils into the DHA and EPA that our body needs. Some people are really poor at this conversion and thus should either eat more fish or consider taking a DHA / EPA supplement.
Foods high in tyramine can cause a hypertensive crisis for people on MAOA inhibitors - and possibly for people who genetically have impaired tyramine metabolism. Learn more about the foods high in this biogenic amine and check to see if you carry the genetic variants that put you at risk. (Member's Article)
Genes play a big role in how quickly you break down alcohol and how fast you eliminate acetaldehyde from your system. Check to see whether you have typical 'drinking genes'. (Member's article)
Methylation Cycle Variants (SNPs)
Should you take folic acid if you carry the MTHFR variants? It turns out that the bigger picture is genetic variants in DFHR, which is upstream of the MTHFR enzyme in the folate pathway. Check your DHFR variants and learn how unmetabolized folic acid may be affecting you. (Member's article)
Riboflavin (vitamin B2) is a water-soluble vitamin that is a cofactor for many enzymes in the body. It is vitally important for energy production in the mitochondria and is also a key component of your body’s detoxification system. Some people may need more riboflavin due to MTHFR or FMO3 genetic variants. (Member's article)
This article digs into the high quality research on the common CBS genetic variants to determine if there is any evidence suggesting everyone should be on a low-sulfur diet. Read through the research and check your genetic data.