Longevity and Healthy Aging

Many of the diseases of aging can be prevented with lifestyle and diet changes. 

Learn how your genes impact healthy aging — and then apply the research-based Lifehacks to optimize your health and prevent the diseases of aging.

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NAD+ article including human studies on NR and NMN

NAD+

Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels, and how this interacts with the aging process.

Alzheimer's

The APOE gene variants are tightly linked with the risk of Alzheimer's disease. Find out whether you carry the APOE risk type for Alzheimer's - and learn what all of us can do via diet and lifestyle to prevent this disease.

Longevity Genes

Centenarians - people who live to be 100+ - have been studied by geneticist to determine how their genes influence longevity. Check your genetic data to see if you carry the FOXO3A and IGF1R variants associated with healthy longevity.

telomeres and aging

Telomeres

Your telomeres are the region at the end of each chromosome that keeps your DNA intact when your cells divide. Telomeres that get too short cause cells to stop dividing, leading to some of the diseases of aging.

Metformin

A decades-old diabetes drug now holds promise for increasing healthspan. Research shows that metformin may reduce the risk of some of the diseases of aging, thus increasing the number of years someone is healthy.

Preventing Alzheimer's

Billions of dollars have been spent in the last couple of decades has been spent on trying to find drugs to stop the tangled accumulation of beta-amyloid plaque without much success. A new direction of research is looking into the ties between circadian rhythm dysfunction and Alzheimer’s disease.

How light at night increases cancer risk

The World Health Organization (WHO) categorizes light at night as a probable carcinogen. Learn why dim light at night increases your risk of breast cancer -- and what you can do to easily reduce this risk.

Fisetin: Anti-aging and antioxidant

Recent research on the flavanoid fisetin shows that it may be a potent supplement for improving health in aging. Fisetin has been shown to act as a senolytic, clearing out senescent cells in animal and cells studies.

How light at night increases cancer risk

The World Health Organization (WHO) categorizes light at night as a probable carcinogen. Learn why dim light at night increases your risk of breast cancer -- and what you can do to easily reduce this risk.

Fisetin: Anti-aging and antioxidant

Recent research on the flavanoid fisetin shows that it may be a potent supplement for improving health in aging. Fisetin has been shown to act as a senolytic, clearing out senescent cells in animal and cells studies.

Klotho Protein

The Klotho protein is involved in many of the diseases of aging. Learn more about this gene and find out how your Klotho variants may impact healthy aging.

Advanced Glycation End Products

One cause of many of the diseases of aging is the buildup of advanced glycation end products (AGEs). Your genes interact with your diet - and cooking methods - in the build up of AGEs.

Genetic variants that protect against Alzheimer's

Just like there are genetic variants that increase the risk of Alzheimer's, there are also variants that protect against this disease. Check your genetic data to get a better picture of your risk factors.

Autophagy

Just like you need to take out the trash and recycle your plastics and cans, your body also needs to clean up cellular waste and recycle proteins. This process is called autophagy, and it is incredibly important in preventing the diseases of aging.