Methylation Cycle

The methylation cycle is a foundational biological pathway that affects many aspects of your wellbeing. In a nutshell, methylation is the donation of a methyl group that is needed for a variety of reactions such as DNA synthesis, neurotransmitter synthesis, and detoxification of some toxins. A methyl group is a carbon plus three hydrogens, and this can be easily used in biological reactions. Many of the molecules that make up your body have a backbone of carbons and hydrogens, so adding another carbon plus three hydrogens (methyl group) can modify the compound. 

Problems within the methylation cycle often cause high homocysteine levels, which is a marker that doctors test for heart disease risk.  Other issues that researchers have linked to methylation cycle problems include an increased risk of depression, anxiety, miscarriage, stroke, and certain cancers. Clinicians often find that methylation cycle problems cause brain fog, mood issues, and fatigue.   

Start with: Check your genetic raw data for MTHFR C677T and A1298C