Does your face flush after a drink or two? The ALDH gene is responsible for the enzyme that breaks down acetaldehyde, which is a toxin that your body produces from alcohol.
While most people can get rid of acetaldehyde fairly quickly, for some, a genetic variant in the ALDH gene causes it to build up. This can cause your face to flush — known as an alcohol flush reaction. It also can make you feel bad when drinking…
Check your genetic data for rs671 (23andMe v4, v5; AncestryDNA):
- A/A: Alcohol flush reaction[ref], also, higher risk of lung cancer from smoking[ref]
- A/G: Alcohol flush reaction
- G/G: typical acetaldehyde metabolism
Members: Your genotype for rs671 is —.
Want more details? Check out the full article on your alcohol drinking gene.
*SNP stands for Single Nucleotide Polymorphism, which is when one of the nucleotide bases (the A, C, G, or Ts) is replaced by a different nucleotide base in a gene. Want to know more about your genes? Read through all the Snips about SNPs.
Related Articles and Topics:
What can you do with your 23andMe or AncestryDNA raw data?
Resources for using your raw genetic data file from 23andMe or AncestryDNA
Genetics on Reddit
Best places to learn more about current genetics research and 23andMe on Reddit
Mast cells: MCAS, genetics, and solutions
Mast Cell Activation Syndrome (Disorder), or MCAS, is a recently recognized disease involving mast cells that misbehave in various ways. Symptoms of MCAS can include abdominal pain, nausea, itching, flushing, hives, headaches, heart palpitations, anxiety, brain fog, and anaphylaxis. Dive into the research on mast cells, genetics, and solutions.
Chronic headaches, sinus drainage, itchy hives, problems staying asleep, and heartburn — all of these symptoms can be caused by the body not breaking down histamine very well. Your genetic variants could be causing you to be more sensitive to foods high in histamine. Check your genetic data to see if this could be at the root of your symptoms.