Snips about SNPs: High Triglycerides and APOA5

The APOA5 gene codes for a lipoprotein that is important in triglyceride metabolism. A variant in the APOA5 gene is linked to higher triglyceride levels and also an increased risk of heart disease.  [ref]

Check your genetic data for rs662799 (23andMe v4, v5; AncestryDNA):

  • A/A: normal
  • A/G: increased triglyceride levels, 16% increase in triglyceride levels [ref]
  • G/G: increased triglyceride levels[ref][ref][ref], 32% increase in triglyceride levels[ref]

 

Learn more about how your genes affect triglycerides and steps that you can take to mitigate the impact.

*SNP stands for Single Nucleotide Polymorphism, which is when one of the nucleotide bases (the A, C, G, or Ts) is replaced by a different nucleotide base in a gene. 

Want more quick bits about your genes? Read through all the Snips about SNPs

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