Snips about SNPs: High Triglycerides and APOA5

The APOA5 gene codes for a lipoprotein that is important in triglyceride metabolism. A variant in the APOA5 gene is linked to higher triglyceride levels and also an increased risk of heart disease.  [ref]

Check your genetic data for rs662799 (23andMe v4, v5; AncestryDNA):

  • A/A: normal
  • A/G: increased triglyceride levels, 16% increase in triglyceride levels [ref]
  • G/G: increased triglyceride levels[ref][ref][ref], 32% increase in triglyceride levels[ref]


Learn more about how your genes affect triglycerides and steps that you can take to mitigate the impact.

*SNP stands for Single Nucleotide Polymorphism, which is when one of the nucleotide bases (the A, C, G, or Ts) is replaced by a different nucleotide base in a gene. 

Want more quick bits about your genes? Read through all the Snips about SNPs

Wishing that you had an easy way to know which Genetic Lifehacks articles apply to you? Get a Genetic Lifehacks Ultimate Cheat Sheet that matches your data to all of the articles available.

Genetic Lifehacks Weekly Update

* indicates required

Leave a Reply

Your email address will not be published. Required fields are marked *