Wondering what your 23 and Me data indicates about your genetic susceptibility to gain weight? I’ve dug into the research to see which genes are associated with obesity — along with specific life hacks that take into account your genetic variants.
We don’t all have the same genetic variants that cause weight gain. Thus, you need to optimize your weight loss plan for the genetic variants that you carry.
No snake-oil, no quick fixes – just science that you can apply to fit your genes
Recent articles on Weight Loss and Your Genes:
Growing up ‘big boned’: MC4R gene and obesity - There are several key players in our body’s regulation of hunger, satiety, and energy expenditure. Leptin and ghrelin are two pivotal hormones involved in our desire to eat. Within that leptin pathway, another key regulator Read more… Digesting Carbohydrates: Amylase variants - Carbohydrate digestion begins in the mouth with an enzyme called amylase. Saliva mixes with your food as you chew it, and the amylase in saliva begins breaking down carbohydrates into simple sugars. Amylase is also Read more… Detoxifying Phthalates: Genes and Diet - There have been several recent studies about phthalates that have piqued my interest. I decided it was time to look into the science behind the stories and see if there really is anything to the Read more… Adiponectin levels, food choices, and genetics - Adiponectin, a hormone discovered in the 1990’s, is secreted by adipose (fat) tissue. It is an anti-inflammatory protein, protective against the effects of low-grade inflammation that are associated with obesity. Although it is made in adipose tissue, Read more… Weight Loss Genetics – DHEA - Dehydroepiandrosterone (DHEA) is one of our body’s most abundantly produced steroid hormones. It is secreted by the adrenal glands, gonads, and in the brain. DHEA acts as both a precursor hormone to testosterone and DHT, Read more… Weight Loss Genetics – PLIN1 - The perilipin 1 gene codes for the protein that covers lipid droplets in fat cells. This coating protects the lipid droplets from the enzymes that break down fats for use as energy in the body. Increased Read more… Weight Loss Genetics – FTO variants - The FTO gene is nick-named the ‘fatso gene’ because of its association with obesity. (Please don’t think that I’m fat-shaming a gene here – researchers really call it that!) There is a really clear link between Read more… UCP2 Gene: Weight Loss Lifehacks - Turning up the heat on your metabolism is the job for UCP2. The UCP2 gene codes for an uncoupling protein that works in the mitochondria (energy powerhouse) of our cells, producing heat through the uncoupling Read more… Weight Loss Genetics – MC4R Revisited - I was catching up on podcasts this weekend and listened to a fascinating one by Dr. Rhonda Patrick. She does the Found My Fitness podcast and had recently interviewed Dr. Panda. The interview was on Read more… Weight loss genetics – GNB3 C825T - I’m geeking out this week and diving deep into the genetics of weight and obesity. One fairly well-studied variant, rs5443, confers a 2x to 3x risk of obesity and is found in the GNB3 gene. Read more… Weight Loss Genetics – Obesity Virus? - When looking at the obesity epidemic around the world, one thing becomes clear: it is complicated! For years we have been told to eat less and exercise more. And while that is good, healthy advice, Read more… Weight Loss Genetics – Ghrelin - This is the beginning of a series of articles looking at the genetic SNPs involved in weight loss. One of the first things to come to mind when wanting to lose weight is controlling appetite. Read more… Adiponectin levels, glucose regulation, and your genes - Adiponectin, a hormone secreted from adipose (fat) tissue, is involved in glucose regulation. Studies show that low levels of adiponectin correlate with insulin resistance and diabetes. Interestingly, although adiponectin is secreted from adipose tissue, levels Read more…