What is Genetic Lifehacks?
Genetic Lifehacks makes it easy to use your genetic raw data to find personalized health and wellness solutions.
- Learn how your genes influence your nutrition, longevity, and wellness.
- Every article shows your genotype report along with multiple research-backed solutions.
- Decide what will work best for you.
Ad-free, science-driven information, empowering you to make informed decisions. Use your genetic raw data from 23andMe, AncestryDNA, and more.
Privacy is paramount. Your genetic data stays on your own computer, not transferred to or stored by Genetic Lifehacks. Member reports are generated in your browser.
What members are saying:
“Life Changing. Words can not express the gratitude and my mind is blown away at how many dots I was able to connect. The knowledge I have been gifted in learning is transformative and every human should be given a genetic test upon birth.”
~ Sarah J.
“Genetic Lifehacks provides relevant and actionnable information for both the layperson and practitioners. Debbie translates very complicated science into understandable concepts for all of us. I can’t recommend this service more highly.”
~ TJ H
“I LOVE LOVE LOVE this site! I show it to all of my medical providers. It’s awesome that it can combine your data from both 23&me and Ancestry DNA. It becomes a beautiful, well laid out, personal map of your own health.”
~ Theresa E.
Latest Articles and Genotype Reports:
Topic: Mitochondrial Health
- Pyruvate Dehydrogenase Deficiency – Mitochondrial Dysfunction and Lactate ProductionPyruvate Dehydrogenase is central to cellular energy production. Learn about its role in energy production, genetic mutations, association with ME/CFS and Long Covid, and strategies to manage its deficiencies.
- Mold Genes: How mold and mycotoxins interact with geneticsExposure to certain kinds of mold can cause chronic, negative health effects. Discover how genetic variants impact the ability to handle mycotoxins.
- Creatine: Boosting Muscles and Increasing Brain PowerCreatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.
Topic: Hormones
- HPA Axis Dysfunction: Understanding Cortisol and Genetic InteractionsCortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
- Thyroid Hormones: Genes, Hypothyroidism, and T4/T3 ConversionThe thyroid is a master regulator controlling many of your body’s systems. It is integral for metabolism and body temperature. Learn more about specific thyroid-related variants and check your genetic raw data.
- Estrogen: How It Is Made and How We Get Rid of ItEstrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.
Topic: Supplements & Genes
- HMB Supplement and Muscle MassHMB – hydroxymethylbutyrate – is a supplement that helps to prevent muscle loss in aging and may help with building muscle when working out.
- DAO Enzyme Supplements: Research Studies and Genetic ConnectionsDAO enzyme supplements work by providing the enzyme needed to break down histamine in food and from the gut microbiome.
- Which Type of Choline Works Best with Your Genes?Choline is an often neglected nutrient essential to a healthy diet. Your genes are important in how much and which types of choline you need.
Topic: Nutrigenomics – Vitamins and Diet
- Manganese: Genetic Interactions, Diet, and SupplementsManganese is an essential mineral needed in the right amount. It is important for health as an antioxidant cofactor, but too much is neurotoxic.
- Are You Getting Too Much Folate?Folate is an essential vitamin with many benefits from getting an adequate amount. However, excess folate from high dose supplements may have potentially detrimental effects.
- Histamine Intolerance: Genetic Report, Supplements, and Real SolutionsGenetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance.
Topic: Disease Prevention
- Aspirin, Colon Cancer Prevention, and GeneticsFor some people with specific genetic variants, aspirin may help to prevent colon cancer. Learn more about what the research says and check your genes.
- Specialized Pro-resolving Mediators (SPMs): The Resolution of InflammationChronic inflammation is at the root of all diseases. New research discusses how pro-resolving mediators are the key to the resolution of inflammation.
- Parkinson’s Disease: Genetics plus Environmental FactorsParkinson’s disease (PD) is not yet fully understood. Researchers think that it is caused by a combo of genetics and environmental factors. Learn more about this disease and the factors that lead to susceptibility.
Topic: Inflammation / Immune Response
- Fibromyalgia: Underlying causes and genetic connectionsLearn about the potential causes of fibromyalgia, including inflammation, genetics, and hypersensitivity to pain, along with overlapping conditions that complicate diagnosis.
- Specialized Pro-resolving Mediators (SPMs): The Resolution of InflammationChronic inflammation is at the root of all diseases. New research discusses how pro-resolving mediators are the key to the resolution of inflammation.
- Asthma Genes: Understanding your genetic pathwaysGenes and environmental factors combine to cause asthma. Learn how your genes impact the pathways involved in the different types of asthma.
Topic: Mood and Brain
- OCD: Obsessive-Compulsive Disorder GenesGenetic variants play a role in susceptibility to obsessive-compulsive disorder. Understanding your genes may help you understand OCD better and help you to target the right treatment.
- HPA Axis Dysfunction: Understanding Cortisol and Genetic InteractionsCortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
- ADHD: Causes, Neurochemistry, and How to Check Your Genetic Raw DataDiscover the complex interplay of genetics and environment in ADHD susceptibility. Learn how circadian rhythm and neurotransmitter genes contribute to the disorder, and how toxicant exposure may increase risk.
Topic: Detoxification & Medications
- CYP2J2: Arachidonic Acid, Inflammation, and Heart DiseaseThe CYP2J2 gene is important in the metabolism of arachidonic acid into either pro- or anti-inflammatory lipid signals.
- Mold Genes: How mold and mycotoxins interact with geneticsExposure to certain kinds of mold can cause chronic, negative health effects. Discover how genetic variants impact the ability to handle mycotoxins.
- Glyphosate Exposure: Genetics and the Impact on Our HealthGlyphosate is the active ingredient in the herbicide Round-Up. A recent study showed that people with CYP1A1 genetic variants are more likely to have problems with acetylcholinesterase inhibition from glyphosate.
Topic: Heart Health
- Salt Sensitivity and High Blood PressureGenetic variants significantly influence individual salt sensitivity, with certain genotypes making people more prone to high blood pressure in response to high salt intake
- Homocysteine: Genetics, High Homocysteine Levels, and SolutionsHigh homocysteine levels are strongly linked to an increased relative risk of cardiovascular diseases. Find out how your genes impact homocysteine levels.
- Niacin and Heart Disease: Genetic InteractionHigher intake of niacin, along with certain genetic variants, has been shown to increase the risk of heart disease. Check your SNPs here.
Topic: Autoimmune Diseases
- Thyroid Hormones: Genes, Hypothyroidism, and T4/T3 ConversionThe thyroid is a master regulator controlling many of your body’s systems. It is integral for metabolism and body temperature. Learn more about specific thyroid-related variants and check your genetic raw data.
- HLA B27: Genetic Variant That Increases Susceptibility to Autoimmune DiseasesThe HLA-B27 serotype is linked to an increased risk of several autoimmune diseases, including ankylosing spondylitis, psoriatic arthritis, and IBD.
- Leaky Gut Genes: Emulsifiers in Processed FoodsEmulsifiers, found in many processed and packaged foods, can trigger an inflammatory response in the intestines based on whether you carry specific genetic variants.
Topic: Methylation Cycle Genes
- Are You Getting Too Much Folate?Folate is an essential vitamin with many benefits from getting an adequate amount. However, excess folate from high dose supplements may have potentially detrimental effects.
- AHCY Gene: Tying together methylation and homocysteineAHCY is a key gene in the conversion of SAH to homocysteine and in the regulation of the SAM/SAH ratio. It also plays an important role in the circadian regulation of gene expression.
- Homocysteine: Genetics, High Homocysteine Levels, and SolutionsHigh homocysteine levels are strongly linked to an increased relative risk of cardiovascular diseases. Find out how your genes impact homocysteine levels.
Topic: Longevity / Healthspan
- HMB Supplement and Muscle MassHMB – hydroxymethylbutyrate – is a supplement that helps to prevent muscle loss in aging and may help with building muscle when working out.
- Aspirin, Colon Cancer Prevention, and GeneticsFor some people with specific genetic variants, aspirin may help to prevent colon cancer. Learn more about what the research says and check your genes.
- Parkinson’s Disease: Genetics plus Environmental FactorsParkinson’s disease (PD) is not yet fully understood. Researchers think that it is caused by a combo of genetics and environmental factors. Learn more about this disease and the factors that lead to susceptibility.
Topic: Circadian Rhythm and Sleep
- Melanopsin: Light response, circadian rhythm, and blue light exposureMelanopsin is the receptor for blue light. It is found in the retina, skin, adipose tissue, and blood vessels. Genetic variants can impact reaction to blue light.
- Histamine, Mast Cell Activation, and Early Morning InsomniaHistamine rising in the early morning hours may cause early waking insomnia. Mast cells and circadian rhythm disruption at the root.
- Restless Leg and Periodic Limb Movement Disorder: Genes and SolutionsMany know the frustration of disrupted sleep due to RLS and periodic limb movement disorder (PLMD). Genes play a role in your risk for these disorders, and there are specific research-based treatments to explore.
Explore by Symptoms, Supplements, Diet, or Pathway:
Symptoms
Supplements
Pathways & Processes
Diseases, Conditions
Lifestyle & Diet
Genes, Proteins
Hormones
Medications
Toxins
Topic: Metabolic Health
- Picking the Right Weight Loss Diet for Your GenesIs there an easy way to compare what diet might be best based on your genotype? Research shows some interesting associations between genotype and diet interactions and weight loss.
- Adenoviruses: Causing Weight Gain and ObesityThere have been several interesting studies linking obesity to a viral infection, specifically an adenovirus. Learn more about this virus and its association with obesity.
- Insulin Resistance and Genetics: Finding the Root CauseGenetics combined with diet causes insulin resistance. While dietary sugar can be involved, genetic research points to BCAAs as having a causal role in IR.
Topic: Traits
- Dyslexia: Genes + Early Life StressorsWhile dyslexia is known to run in families, the role of genetics in dyslexia is still being determined. Here is a quick look at some of the genes involved in dyslexia, affecting around 10% of the population.
- Mosquito Bite Genes: Are you a mosquito magnet?Do you feel like you are a magnet for mosquitoes? Genetic variants do play a role in how attractive you are to mosquitoes.
- Will you go bald? Genetics and hair lossWhat causes male pattern baldness? A combination of genetics, nutrition, and environmental toxins come together to form the risk factors for baldness. But genetics really seems to rule the roost here.
Topic: Pregnancy / Infertility
- Trying to get pregnant? Targeted Approaches to Improving Egg QualityTrying to get pregnant? Healthy eggs are vital for a successful pregnancy. Discover four key ways to improve your egg quality, according to research studies.
- Folate Optimization: MTHFR and FertilityMTHFR variants affect the conversion of folate into the active form. Learn how this can affect you if you are trying to get pregnant.
- Genetic Causes of Male InfertilityAlmost 10% of couples worldwide struggle with infertility. Learn more about your genetic susceptibility and dig deeper into the lifestyle factors that could affect your sperm.
My Story…
Hi! I’m Debbie Moon. Welcome to Genetic Lifehacks.
When I first had my genetic data sequenced, I was both amazed at the research available in academic journals and frustrated by the difficult language and disconnected topics.
Genetic Lifehacks began as a way to share what I was learning about genetics with my family and friends.
My goal has always been to freely share information so that everyone can benefit.
As the website grew in popularity, I decided that I needed to know more… both more about genetics and more about how the pieces of the biological systems fit together. Since my undergraduate degree was in engineering, I went back to school and received my Master’s degree in Biological Sciences from Clemson University in 2019.
Now a full-time endeavor, Genetic Lifehacks has reached over 2.5 million readers, equipping people to use their genetic data to optimize their health.
~ Debbie Moon, Founder of Genetic Lifehacks