Key takeaways: ~ Phase I and phase II detoxification are the primary ways your body eliminates toxins. ~ Genetic variants in these pathways affect how well you detoxify certain substances. Detoxification and Genetic Pathways: Your body is remarkably capable of ridding itself of harmful substances through complex detoxification pathways. In today’s world, we are all exposed to various toxicants (manufactured toxins) through pesticide residue, air pollution, skin care products, and medications. Additionally, our bodies break down and eliminate substances made and used within ourselves, as well as natural plant compounds. All of these processes rely on intricate systems in our bodies that metabolize and eliminate toxins. Many people have genetic variants that impact how medications and toxicants are broken down and eliminated. Our genes make us unique, and one difference between people is seen in the differences in the phase I and phase II detoxification pathway genes. Understanding where you have a genetic sensitivity — and then optimizing to avoid specific toxicants or drugs — is the key here. To better understand this process, let’s first explore how phase I … Continue reading Detoxification: Phase I and Phase II Metabolism