CYP2D6: Metabolism of many OTC and prescription medicines

Say you aren’t feeling well, have had a cold for a week, and can’t sleep…  You’re just plain miserable.  And in your sleep deprived state, you decide to take some Nyquil (or another cough syrup containing dextromethorphan). Some people may get relief and finally get…

CYP3A4 and CYP3A5: How genes impact prescription medications

Our bodies break down (metabolize) drugs and other toxins through a group of enzymes known as the CYP450 family. Different CYP enzymes break down different substances, and we all carry genetic variants that can impact whether we metabolize a drug quickly or slowly. The…