Understand your genetic data and optimize your health and diet.

Millions of genetics research papers have been published. But… No one is putting that knowledge into practice!

My goal is to help you understand how your genes impact your health and wellness – and how to apply that knowledge.

I’ll make you smarter (about genetics). All you have to do is dive in and get started.

Autoimmune Diseases:

More articles in Autoimmune >>>

Inflammation and Immune Response:

  • Beating Flu Season
    Are you more genetically susceptible to the flu? Will Tamiflu work for you? Learn how your genes play a role and discover research-backed natural options to beat the flu.
  • Estrogen, histamine, and mast cell connections
    Mast cells can be more easily triggered in the presence of high estrogen or estrogen-mimicking compounds. Histamine can also trigger mast cell degranulation. Together, this can cause a lot of symptoms related to mast cell activation.
  • IL13 Genomics: Elevating Th2 Immune Response
    Interleukin-13 (IL-13) is a signaling molecule important in the immune response. Excessive IL-13 can tip you towards a Th2 dominant immune response, and variants increase the risk of allergies and asthma.

More articles in Inflammation and Immune >>>

Mood and Brain:

  • HPA Axis Dysfunction: Cortisol and Stress
    Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
  • Intelligence Genes
    Hundreds of identified genes influence intelligence, from IQ scores to musical ability. Learn more about your intelligence strengths and ways to enhance your cognitive function.
  • Anxiety: Genetics and personalized solutions
    When it comes to anxiety, genetic variants combine with environmental factors (nutrition, sleep, relationships, etc) when it comes to anxiety. Understanding your anxiety genes can help you figure out which pathways to target.

>>>More in Mood and Brain >>>

Vitamins and Foods:

>>> More in Vitamins and Foods >>>

Heart Health:

>>>More in Heart Health >>>

Supplements & Genes

>>>More in Supplement Research >>>

Explore by Topic:

Over 350 articles explaining genetics, health, longevity, and optimization:

Popular search terms: Histamine, MTHFR, Depression, COMT

Disease Prevention:

  • Beating Flu Season
    Are you more genetically susceptible to the flu? Will Tamiflu work for you? Learn how your genes play a role and discover research-backed natural options to beat the flu.
  • Essential Tremor: Causes and Possible Solutions
    Essential tremor (ET) is a neurological disease causing involuntary shaking in places of the body while performing tasks such as writing or eating. Learn more about this disease and discover the genetic causes of ET.
  • Dry Eyes: Using Genomics to Find Solutions
    Do you suffer from dry eyes? Learn about current research-backed solutions and the genetics links that could increase your susceptibility.

More in Disease Prevention >>>

Metabolic Health:

More in Metabolic Health >>>

Methylation Cycle:

  • Creatine: Boosting Muscles and Increasing Brain Power
    Creatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.
  • Migraines: Genes, Root Causes, and Personalized Solutions
    Your genes play a role in your susceptibility to migraines. Find out what is going on when you have a migraine and solutions that fit your genes.
  • What is MTHFR? Is it important?
    The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.

More in Methylation Cycle >>>


  • Detoxifying Phthalates: Genes and Diet
    Phthalates are a type of chemical used as plasticizers to make plastics more pliable. There has been a lot of research on the endocrine-disrupting effects of phthalates. Your genetic variants may impact whether phthalates are a problem for you.
  • CYP2B6: Genetic variants impacting medication reactions
    The CYP2B6 enzyme is part of the body’s first line of defense in detoxifying and breaking down certain and important for metabolizing several medications. Genetic variants of this enzyme can either speed up or slow down its function.
  • Mercury Detoxification: Genomics and Solutions
    What are the physiological effects of mercury and how does the body eliminates it? Discover how genetic variants play a role in how quickly you excrete mercury.

More in Detoxification >>>


  • Genetic Causes of Male Infertility
    Almost 10% of couples worldwide struggle with infertility. Learn more about your genetic susceptibility and dig deeper into the lifestyle factors that could affect your sperm.
  • Recurrent miscarriage: Genes and Inflammation
    Learn about how genetic variants in certain inflammatory cytokines can increase or decrease the risk of recurrent miscarriage.
  • PCOS: Genetics and Root Causes
    Polycystic ovarian syndrome (PCOS) is an endocrine disorder causing an increase in androgen hormone production in women. It also increases the risk of infertility. PCOS affects 5 -10% of premenopausal women, and genetics plays a large role in whether you have PCOS.

More in Fertility >>>


  • Genetics and Color Blindness
    Do you have difficulty seeing some colors? Discover how variants in genes related to color blindness may mean we all see things a bit differently.
  • Does cilantro taste like soap to you?
    Are you one of those people that thinks cilantro tastes like soap? If so, it may be due to a genetic variant.
  • Dyslexia: Genetic Connections
    While dyslexia is known to run in families, the role of genetics in dyslexia is still being determined. Here is a quick look at some of the genes involved in dyslexia, affecting around 10% of the population.

More in Traits >>>

My Story…

Hi! I’m Debbie Moon. Welcome to Genetic Lifehacks.

When I first had my genetic data sequenced, I was both amazed at the research available in academic journals and frustrated by the difficult language and disconnected topics.

Genetic Lifehacks began as a way to share what I was learning about genetics with my family and friends.

My goal has always been to freely share information so that everyone can benefit.

As the website grew in popularity, I decided that I needed to know more… both more about genetics and more about how the pieces of the biological systems fit together. Since my undergraduate degree was in engineering, I went back to school and received my Master’s degree in Biological Sciences from Clemson University in 2019.

Now a full-time endeavor, Genetic Lifehacks has reached over 2.5 million readers, equipping people to use their genetic data to optimize their health. 

Debbie Moon, Founder of Genetic Lifehacks