Understand your genetic data and optimize your health and diet.

Millions of genetics research papers have been published.

But… No one is reading them or putting the wealth of knowledge into practice!

My goal is to help you understand how your genes impact your health and wellness. My motto is simple:

Learn. Experiment. Optimize.

I’ll make you smarter (about genetics). All you have to do is dive in and get started.

Heart Health:

>>>More in Heart Health >>>

Vitamins and Foods:

  • Magnesium deficiency? Genes that Impact Magnesium Levels
    Are your magnesium levels low? Understanding your genes can help you decide whether you may need more magnesium in your diet or via supplements.
  • Biotin Deficiency: Check your Genes
    Biotin, also known as vitamin B7 or vitamin H, is a cofactor that aids in the metabolism of fats, carbohydrates, and proteins. Biotin deficiency due to diet is pretty rare, but there are genetic variants that can increase your risk for biotin deficiency or insufficiency.
  • Lactose Intolerance Genes
    Your genes control whether you are likely to produce lactase as an adult. Check your 23andMe or other genetic data to see if you are likely to enjoy a big glass of milk.

>>> More in Vitamins and Foods >>>

Inflammation and Immune Response:

  • IL13 Genomics: Elevating Th2 Immune Response
    Interleukin-13 (IL-13) is a signaling molecule important in the immune response. Excessive IL-13 can tip you towards a Th2 dominant immune response, and variants increase the risk of allergies and asthma.
  • Acupuncture and Genomics: Who is more likely to respond?
    Have you tried acupuncture? This treatment has been around for thousands of years but did you know that your genetic variants can impact how well you respond?
  • Tendinitis Genes
    Do you have problems with your tennis elbow, rotator cuff, knees, or Achilles tendon? Discover how your genes influence the risk of having tendon problems.

More in Inflammation and Immune >>>

Mood and Brain:

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Explore by Topic:

Over 350 articles explaining genetics, health, longevity, and optimization:

Popular search terms: Histamine, MTHFR, Depression, COMT

Disease Prevention:

  • Gilbert Syndrome
    Gilbert’s syndrome is an inherited condition where the body doesn’t break down bilirubin efficiently. Discover the benefits of higher bilirubin levels in this syndrome and some possible risks.
  • Primary Sclerosing Cholangitis
    Primary sclerosing cholangitis (PSC) is a life-altering condition that damages the bile ducts, thus impacting the liver. Learn about the research and heritability of this disabling disease.
  • Genetic Superpowers Report
    This Genetic Superpowers Report looks at the positive side of genetic variants. Everyone has some kind of genetic superpower, and hopefully, this report will highlight yours!

More in Disease Prevention >>>

Metabolic Health

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Methylation Cycle:

  • Migraines: Genes, Root Causes, and Personalized Solutions
    Your genes play a role in your susceptibility to migraines. Find out what is going on when you have a migraine and solutions that fit your genes.
  • What is MTHFR? Is it important?
    The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.
  • CBS Gene Variants and Low Sulfur Diet
    Some clinicians recommend a low sulfur diet for people with CBS mutations. Find out what the research shows – and why that recommendation is not backed up. (Member’s article)

More in Methylation Cycle >>>


  • CYP2B6: Genetic variants impacting medication reactions
    The CYP2B6 enzyme is part of the body’s first line of defense in detoxifying and breaking down certain and important for metabolizing several medications. Genetic variants of this enzyme can either speed up or slow down its function.
  • Mercury Detoxification: Genomics and Solutions
    What are the physiological effects of mercury and how does the body eliminates it? Discover how genetic variants play a role in how quickly you excrete mercury.
  • CYP2C19 – Metabolizing medications
    Several popular drugs such as Prilosec, Nexium, and Plavix are metabolized by the CYP2C19 enzyme. There are important genetic variants in the CYP2C19 gene that changes how fast or slowly these drugs are broken down. Learn how these variants might affect their efficacy. (Member’s article)

More in Detoxification >>>


  • Genetic Causes of Male Infertility
    Almost 10% of couples worldwide struggle with infertility. Learn more about your genetic susceptibility and dig deeper into the lifestyle factors that could affect your sperm.
  • Recurrent miscarriage: Genes and Inflammation
    Learn about how genetic variants in certain inflammatory cytokines can increase or decrease the risk of recurrent miscarriage.
  • PCOS: Genetics and Root Causes
    Polycystic ovarian syndrome (PCOS) is an endocrine disorder causing an increase in androgen hormone production in women. It also increases the risk of infertility. PCOS affects 5 -10% of premenopausal women, and genetics plays a large role in whether you have PCOS.

More in Fertility >>>

My Story…

Hi! I’m Debbie Moon. Welcome to Genetic Lifehacks.

When I first had my genetic data sequenced, I was both amazed at the research available in academic journals and frustrated by the difficult language and disconnected topics.

Genetic Lifehacks began as a way to share what I was learning about genetics with my family and friends. My goal has always been to freely share information so that everyone can benefit.

As the website grew in popularity, I decided that I needed to know more… both more about genetics and more about how the pieces of the biological systems fit together. Since my undergraduate degree was in engineering, I went back to school and received my Master’s degree in Biological Sciences from Clemson University.

Now a full-time endeavor, Genetic Lifehacks has reached over 2 million readers, equipping people to use their genetic data to optimize their health. 

Debbie Moon, Founder of Genetic Lifehacks