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Use your genetic data to optimize your health and wellness.
Connect to your raw data from 23andMe, AncestryDNA, MyHeritage, Sequencing.com, TellMeGen, or other DNA test, and see what your own genes show about the food, supplements, and lifestyle changes that are a good fit for you.
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- 11 years of reading the studies, making connections, and writing them up
- 6+ million readers
- 22,000 members and newsletter subscribers
- 410+ genotype reports with detailed articles that are constantly updated as new research comes outs
Explore by topic hub:
Latest Genotype Reports:
- Methylated B Vitamins: Are They Really Better? (Genetics, Forms, and What the Studies Show)
Are methylated B vitamins better? It depends—methylfolate vs folic acid, B12 forms, B6/P5P, riboflavin for MTHFR, plus SNPs and studies. - Arginine: Genetics, Nitric Oxide, Immune Response, and Ammonia Clearance
Learn how ARG1 and ARG2 variants influence arginine levels, nitric oxide, and urea-cycle balance—plus food, L-arginine vs citrulline, and safety trade-offs. - TNF-alpha: Inflammation, Chronic Diseases, and Genetic Susceptibility
TNF-alpha is a key inflammatory cytokine linked to autoimmune, cardiovascular, mood, and neurodegenerative diseases. Learn how TNF gene variants affect your risk and potential natural TNF inhibitors. - ABCC4 (MRP4) Gene: Drug Transport, Genetic Variants, and Medication Response
Learn how the ABCC4 (MRP4) gene transports drugs, toxins, cAMP, and prostaglandins. Explore common variants, medication interactions, and factors that alter ABCC4 activity. - Hypophosphatasia (HPP) and the ALPL Gene
Hypophosphatasia (HPP) is a genetic disorder caused by ALPL mutations that lower alkaline phosphatase (ALP), leading to bone, dental, and vitamin B6-related issues. Learn how low ALP is diagnosed and supported in adults. - NQO1 Gene: Metabolism of Quinones, Benzene, and More
The NQO1 gene codes for an important enzyme in phase II detoxification. This enzyme is responsible for metabolizing the cancer-causing benzene (e.g. from air pollution) and cigarette toxins. Learn more and check your genes. (Member’s article) - Magnesium Deficiency? Genes that Impact Magnesium Levels
Genes like TRPM6, TRPM7, and CNNM2 affect how well your body absorbs and retains magnesium. See your genotype report for Mg deficiency and types of supplements. - Norepinephrine: Focus, stress, genetics, and brain function
Discover how norepinephrine and your genes affect ADHD, ME/CFS, long COVID, POTS, and mood, plus evidence‑based ways to support healthy norepinephrine balance. - Drug-Induced Depletions: Medications and Missing Micronutrients
Common medications can deplete micronutrients, especially when combined with a genetic susceptibility to lower levels of certain vitamins or minerals. If you’re on any prescription drugs, check your genes and consider testing your micronutrient levels.
Recently updated articles + genotype reports:
Staying up to date with new research is important! Check out these genotype reports that have been updated:
Caffeine Metabolism and Your Genes
PFAS, Mitochondrial Function, Immune Response, and Genetics
Summary Reports, Personalized Reports, & Lifehacks Reports
Gingivitis: The Genetic Connection between Gum Disease, Inflammation, and Overall Health
FOLR1 and FOLR2: Transporting Folate, Folinic Acid, and Folic Acid into Cells
Methylated B Vitamins: Are They Really Better? (Genetics, Forms, and What the Studies Show)
Gilbert’s Syndrome: UGT1A1, Triggers, and What to Avoid
COMT and Supplements: What to Take or Avoid with Slow or Fast COMT
My Story…
Hi! I’m Debbie Moon, founder of Genetic Lifehacks.
When I first had my genetic data sequenced, I was both amazed and frustrated: amazed by all of the genetic research available in academic journals, but frustrated by the disconnected topics and lack of accessibility.
I started Genetic Lifehacks to bridge the gap — to help everyone understand how their genes influence their health, diet, and longevity with practical and useful information based on current research studies.
With my undergraduate degree in engineering as a foundation and a Master’s degree in Biological Sciences from Clemson University (2019), I’ve built Genetic Lifehacks into a platform that has helped over 5 million readers and 19,000+ members to optimize their health through understanding their genetics.
~ Debbie
Learn more About Genetic Lifehacks