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How genetics influences weight loss with aerobic exercise

Skinny Genes: Weight Loss from Aerobic Exercise

Have you ever thought, “If I just exercised a little more, I could lose that extra 20 pounds!” A new study published in September 2024 looked at the relationship between weight loss, aerobic exercise, and genetics. It attempts to answer the question, “Who loses weight and why? Losers and gainers: … Read more

Creatine Synthesis, Foods high in creatine, creatine benefits

Creatine: Boosting Muscles and Increasing Brain Power

Creatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.

ACTN3 fast muscle type genetics

ACTN3 Gene: Deficiency and Muscle Type

The ACTN3 gene codes for actinin alpha-3, a protein found in fast-twitch muscles. Some people don’t produce this protein, which changes the composition of their muscles. Elite athletes may be limited by this genetic change.

PPAR-Delta: Burning off the Fat

PPARδ is a key player in how and when your muscles burn fat for fuel. Genetic variants in the PPARD gene impact how well your muscles utilize fatty acids. These variants also impact how much of a fat-burning benefit you get from exercise.

Exercise Report

Utilize our Athletics Summary Reports with your 23andMe or AncestryDNA genetic data to see which articles may be most relevant to you. These summaries are attempting to distill the complex information down into just a few words. Please see the linked articles for details and complete references. (Member’s article)

Genetic Influence on Exercise Motivation and Intensity

Motivation to exercise? It’s genetic.

A study in the journal Behavioral Brain Research paints a fascinating picture of why some people are more motivated to exercise. The study looked at the dopaminergic system to see how people’s genetic variants could alter the ‘reinforcing value’ of exercise.

HIF-1a: Hypoxia, Cancer, and Athletic Superpowers

The hypoxia-inducible factor-1 alpha (HIF1A) gene codes for a transcription factor, that responds to the amount of oxygen available to the cell. This is important in cancer prevention, and several HIF1A genetic variants alter the susceptibility to several types of cancer.

Genetic variants that affect athletic performance, AMPD1, ACTN3, NOS3, MSTN gene

Athletic Performance Genes

Genes control the formation, composition, and type of muscle fiber. Learn how to optimize your training when genetics comes into play, affecting muscle composition and endurance.