Magnesium Deficiency? Genes that Impact Magnesium Levels
Genes like TRPM6, TRPM7, and CNNM2 affect how well your body absorbs and retains magnesium. See your genotype report for Mg deficiency and types of supplements.
Nutrients
Nutrigenomics: Genetics + Nutrients
Your genes influence how well you absorb different vitamins and minerals, and your genes also interact with how your cells use nutrients. Genetic data can give you a starting point to know where you may need more – or less – of a specific nutrient. It can also point to problems with specific foods, like dairy, or with a component of foods, like histamine or tyramine.
Here you will find the tools you need to dial in your nutrition. This isn’t a one-size-fits-all approach. Instead, you’ll learn which nutrients may be more important for you, and then you can decide how best to implement the many possible solutions.
Popular topics
- Histamine intolerance
- MTHFR and folate
- Which type of choline works best with your genes?
- Vitamin A and converting beta-carotene
- Lactose intolerance genes
- Thiamine, Biotin, or Vitamin B6
Member tools:
DNA summary report – Nutrients Summary Report
Supplements and Your Genes
Latest articles on Vitamins, Nutrients, and Genetics:
Drug-Induced Depletions: Medications and Missing Micronutrients
Common medications can deplete micronutrients, especially when combined with a genetic susceptibility to lower levels of certain vitamins or minerals. If you’re on any prescription drugs, check your genes and consider testing your micronutrient levels.
TRPV1 Gene: Receptor for Spicy Foods, Sensing Cold, and CBD Oil
Learn how the TRPV1 gene shapes your reaction to spicy foods, pain, temperature, neuroinflammation and CBD oil, plus see how your genetic variants may affect tolerance and health.
Which Type of Choline Works Best with Your Genes?
Which choline supplement works best based on your PEMT, MTHFD1, and CHKA genes? Compare citicoline, alpha-GPC, PC, and betaine.
MMUT Gene Variants & Methylmalonic Acid: B12 Status & Genetics
MMUT gene variants affect how your body uses B12 for mitochondrial energy. Learn how MMA testing reveals intracellular B12 deficiency and which form of B12 can help.
Histamine Intolerance Genetics: DAO & HNMT Genes, Supplements
Genetic variants in DAO and HNMT genes affect histamine breakdown. Check your AOC1, HNMT, and HDC genotype. Low-histamine diet, DAO supplements, and more.
Thiamine: Genomics, Cellular Energy, and Cognitive Function
Thiamine (vitamin B1) is essential for energy production and brain function. Learn how SLC19A2, SLC19A3, and other genes affect your need for thiamine.
Vitamin B5 (Pantothenic Acid): Genetics, Deficiency, and Neurodegenerative Disease
Pantothenic acid (vitamin B5) is essential for coenzyme A synthesis and brain energy. Learn about B5 deficiency, PANK2 mutations, and links to Alzheimer’s.
Zinc, Genetics, and Your Risk for Depression, Infection, or Diabetes
Zinc is essential for immunity, skin, mood, and blood sugar, and your genes can change how much you need. Learn how zinc transporter variants affect your optimal intake.
BChE gene: Nightshade sensitivity, Anesthesia risk
BCHE variants can lower butyrylcholinesterase activity. See implications for anesthesia, nightshades, pesticide susceptibility, immunity, and ghrelin.
Vitamin B6: Genetics, Absorption, and Deficiency
Vitamin B6 is an important co-factor in hundreds of different enzymatic reactions. Low levels of B6 are linked to an increased risk of diabetes, cardiovascular disease, neurodegenerative diseases, and cancer. B6 is also essential for reducing oxidative stress and inflammation.
Manganese: Genetic Interactions, Diet, and Supplements
Manganese is an essential mineral needed in the right amount. It is important for health as an antioxidant cofactor, but too much is neurotoxic.
Molybdenum: Genetic Connections, Sulfur Metabolism, and Cofactor Deficiency
Molybdenum is a trace mineral needed in the right amounts for sulfur detoxification and the formation of uric acid.
Tyramine Intolerance: Symptoms, High-Tyramine Foods, and Genetics
Tyramine intolerance happens when you can’t break it down. Too much tyramine can lead to a hypertensive crisis. Learn more and check your genetic raw data for results.
Very Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
VLCAD deficiency causes the mitochondria to be unable to use long-chain fatty acids for energy production. This can result in hypoglycemia or mitochondrial dysfunction.
Oxalates: What Your Genes and Diet Say About Oxalate Health Issues
Green smoothies have been a health fad for quite a while now, but these health drinks can be a double-edged sword for some people due to their high oxalate content. Find out if you are genetically prone to kidney stones and what to do about it.
MTHFR Gene Explained: C677T and A1298C Variants, Testing, and Solutions
The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. It is a key gene in the methylation cycle.
Vitamin C: Nutrigenomics, Transport, and Genetic Deficiency
Genetic variants in SLC23A1 and SLC23A2 affect vitamin C absorption and blood levels. Learn how your genes affect your need for vitamin C.
Homocysteine: Genetics, High Homocysteine Levels, and Solutions
High homocysteine levels are strongly linked to an increased relative risk of cardiovascular diseases. Find out how your genes impact homocysteine levels.
FOLR1 and FOLR2: Transporting Folate, Folinic Acid, and Folic Acid into Cells
Genetic variants in the FOLR1 and FOLR2 genes (folate receptors alpha and beta) can impact folate in the brain and in the immune response.
Carnitine: Genetic Variants Affecting Mitochondrial Energy and Health
Learn how carnitine powers cellular energy, supports organ health, and influences metabolism. Discover its benefits for brain, liver and immune function, plus how genetics affect your carnitine needs.
DHFR and MTHFR: Folic Acid Metabolism
Methylfolate and folic acid—what’s the difference? Learn how DHFR and MTHFR variants affect folic acid metabolism, unmetabolized folic acid, cancer and autism risk, BH4 recycling, and how to choose the right supplement for your genes.
Pregnancy: How Your Genes affect the Nutrients You Need
Pregnancy is a time of increased nutritional needs, and your genes can help you dial in your diet to prevent nutrient deficiencies.
Casein and Cow’s Milk Allergies
Cow’s milk allergy can be due to your immune system responding to casein or β-lactoglobulin. Genetic variants in immune-system genes increase susceptibility – along with environmental factors.
Vitamin K: Bone Strength, Blood Clots, Calcification, and Genetics
Genetic variations cause people to have higher or lower levels of vitamin K, which can affect blood clotting. Learn more about the genes that affect vitamin K and how it relates to your genetic raw data.