Manganese: Genetic Interactions, Diet, and Supplements
Manganese is an essential mineral needed in the right amount. It is important for health as an antioxidant cofactor, but too much is neurotoxic.
Are you getting the right form of vitamin A? Do you need more biotin than most people? What about folate? Knowing which specific nutrients you may ‘genetically’ need more of can be the key to solving health issues or optimizing wellness.
Here you will find the tools you need to dial in your nutrition. This isn’t a one-size-fits-all approach. Instead, you’ll learn which nutrients may be more important for you, and then you can decide how best to implement the many possible solutions.
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Manganese is an essential mineral needed in the right amount. It is important for health as an antioxidant cofactor, but too much is neurotoxic.
Folate is an essential vitamin with many benefits from getting an adequate amount. However, excess folate from high dose supplements may have potentially detrimental effects.
Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance.
Choline is an often neglected nutrient essential to a healthy diet. Your genes are important in how much and which types of choline you need.
AHCY is a key gene in the conversion of SAH to homocysteine and in the regulation of the SAM/SAH ratio. It also plays an important role in the circadian regulation of gene expression.
The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.
Creatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.
Genetic variants in the FOLR1 and FOLR2 genes (folate receptors alpha and beta) can impact folate in the brain and in the immune response.
Biotin, also known as vitamin B7 or vitamin H, is a cofactor that aids in the metabolism of fats, carbohydrates, and proteins. Biotin deficiency due to diet is pretty rare, but there are genetic variants that can increase your risk for biotin deficiency or insufficiency.
Green smoothies have been a health fad for quite a while now, but these health drinks can be a double-edged sword for some people due to their high oxalate content. Find out if you are genetically prone to kidney stones and what to do about it.
There are several genes that can influence your absorption, transport, and need for vitamin B12. Some people need higher amounts of B12, and some people thrive on different forms of B12. Take a look at your genetic data to see if you should up your intake of B12.
CoQ10, or ubiquinone, is an integral part of mitochondrial energy production. It is also used as a lipid-soluble antioxidant. Learn how age and genes affect it.
Mutations in ATP7B can cause copper dysregulation and Wilson’s disease. People carrying one copy of the mutation may also have subtle changes.
Fructose intolerance can be due to a rare mutation in the ALDOB gene or it can be due to reduced intestinal absorption.
Riboflavin, or vitamin B2, is an essential cofactor for many biological pathways. Learn how to check your genetic raw data to see if you may need more riboflavin.
Nickel allergy can cause sensitivity to foods that contain nickel. Learn about how genes increase susceptibility and solutions.
Drinking alcohol is often a problem for people with histamine intolerance. Learn about the pathways that are involved and how to avoid alcohol-induced reactions.
Genetic variants of the BChE gene decrease its enzyme’s activity. This can lead to various and seemingly unconnected consequences…such as an increased risk for Parkinson’s or food sensitivity to potatoes.
Are your magnesium levels low? Understanding your genes can help you decide whether you may need more magnesium in your diet or via supplements.
Your genes control whether you are likely to produce lactase as an adult. Check your 23andMe or other genetic data to see if you are likely to enjoy a big glass of milk.
Tryptophan is an amino acid that the body uses to make serotonin and melatonin. Genetic variants can impact the amount of tryptophan that is used for serotonin. This can influence mood, sleep, neurotransmitters, and immune response.
Like most nutrients, our genes affect how vitamin C is absorbed, transported, and used by the body. It can influence your risk for certain diseases and make a difference in the minimum amount of vitamin C you need to consume each day.
Also known as vitamin B1, thiamine is essential for energy production and brain function. Learn how your genes influence your need for thiamine.
Learn why zinc is important for your immune system and so much more. Find out how your genes impact your need for zinc and discover ways of boosting your zinc status.
Some clinicians recommend a low sulfur diet for people with CBS mutations. Find out what the research shows – and why that recommendation is not backed up. (Member’s article)