Supplemental Melatonin
Melatonin is important for setting your circadian rhythm and for immune health. Dig into the details on melatonin supplements, scientific research, and more.
Sleep & Circadian Rhythm
Your circadian rhythm is the 24-hour internal clock which drives many important aspects of your health. Learn about how your genes impact your circadian rhythm and how this interacts with other health topics.
Depression, Genetics, and Circadian Rhythm
For some people, circadian disruption can be chronic – and at the heart of depression or mood disorders. Genetic variants play a role in this susceptibility. Fortunately, there are solutions that may help.
Lithium orotate: A natural mineral that affects mood, Alzheimer’s disease, and aging
Researchers found that Texas counties with higher levels of lithium in their groundwater had less of an increase in Alzheimer’s rates compared with counties that had lower levels of lithium. This isn’t a total surprise since previous studies had linked lithium to a decreased risk of dementia, but it is a great confirmation at a large scale population level.
Using your genetic data to solve sleep problems
An overview explaining how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes. Start here and then dive deeper into the specific topics.
Circadian Rhythm and Your Immune Response to Viruses
Your circadian rhythm influences your immune response. Learn how this rhythm controls white blood cell production and why melatonin is important in protecting against viral and bacterial infections.
Sleep & Circadian Rhythm Topic Summary
Utilize our Sleep & Circadian Rhythm Topic Summary Reports with your 23andMe or AncestryDNA genetic data to see which articles may be most relevant to you. These summaries are attempting to distill the complex information down into just a few words. Please see the linked articles for details and complete references. (Member’s article)
Increased Slow Wave Sleep
Find out how genes interact with your lifestyle in controlling the amount of deep sleep you get each night. Check out your genetic variants and hack your sleep. (Member’s article)
Genetics of Seasonal Affective Disorder
Seasonal Affective Disorder (SAD) is characterized by recurrent depression with a change in the season usually in fall/winter for most. Scientists think this is possibly due to an aberrant response to light – either not enough brightness to the sunlight or not enough hours of light. Your genes play a big role in this responsiveness to light.
Restless Leg and Periodic Limb Movement Disorder: Genetics and Solutions
Many know the frustration of disrupted sleep due to RLS and periodic limb movement disorder (PLMD). Genes play a role in your risk for these disorders, and there are specific research-based solutions to try.
Heart disease, cancer, diabetes: The BMAL1 gene ties together the “Big 3”
A core circadian rhythm gene, BMAL1, influences heart disease risk, diabetes, and cancer. Check your genes and learn how to mitigate the risk.
How natural supplements can change circadian gene expression
Did you know that some supplements change the expression of your core circadian clock genes? Your core circadian rhythm genes are foundational to your health, and some supplements alter that rhythm.
Melatonin: Key to Health and Longevity
More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.
Blue-blocking Glasses: Why? Which ones?
An easy way to improve sleep and increase melatonin production at night is to wear blue light blocking glasses before bed. Explore the research on why this is so important, and learn about the different options available for blue-blocking glasses.
Do you wake up at 4 am? Genetics and early waking insomnia
Seeing 3:30 or 4:00 on your clock each morning? There could be a physiological reason for this. Learn about the genetic variants linked to early waking insomnia and the connection to depression. (Member’s article)
Bipolar disorder, depression, and circadian clock genes
New research shows that depression and bipolar disorder are linked to changes or disruption in circadian genes. Some people carry genetic variants in the circadian genes that make them more susceptible to circadian disruption.
Leveraging your gut microbiome to change your gene expression
Your gut microbiome influences the expression of your core circadian rhythm genes.