Serotonin 2A receptor variants: psychedelics, brain aging, and Alzheimer’s disease
Learn how new research on brain aging and dementia connects the serotonin 2A receptor with psychedelics, brain aging and Alzheimer’s.
Alzheimer’s
TREM2 and Alzheimer’s Disease Risk
The TREM2 gene is important in how the brain’s immune system functions. Learn how variants in this gene impact the risk for Alzheimer’s disease.
SOD1: Genetic Variants in Our Antioxidant Defense System
Our body has built-in antioxidants that fight against cellular stress. The superoxide dismutase enzyme fights against oxidative stress in your cells.
Lithium orotate: A natural mineral that affects mood, Alzheimer’s disease, and aging
Researchers found that Texas counties with higher levels of lithium in their groundwater had less of an increase in Alzheimer’s rates compared with counties that had lower levels of lithium. This isn’t a total surprise since previous studies had linked lithium to a decreased risk of dementia, but it is a great confirmation at a large scale population level.
A Klotho Gene Variant Reduces Alzheimer’s Risk for APOE E4 Carriers
The Klotho protein is involved in many of the diseases of aging. Learn more about this gene and find out how your Klotho variants may impact healthy aging.
Alzheimer’s and APOE genotype
The APOE gene variants are tightly linked with the risk of Alzheimer’s disease. Find out whether you carry the APOE risk type for Alzheimer’s – and learn what all of us can do via diet and lifestyle to prevent this disease.
Prions: When proteins go awry
Prions are able to infect, causing the normal protein around them to also misfold. These misfolded proteins aggregate to cause neurogenerative disease. Susceptibility to prion diseases depends in part on your genes.
Genetic Mutations that Protect Against Alzheimer’s Disease
Just like there are genetic variants that increase the risk of Alzheimer’s, there are also variants that protect against this disease. Check your genetic data to get a better picture of your risk factors. (Member’s article)
How your melatonin receptor gene impacts Alzheimer’s risk and night shift work
Shift work and ‘social jet lag’ are linked to an increased risk for several chronic diseases. A genetic variant in the MTNR1A gene impacts melatonin receptors in the brain. (Member’s article)
Alzheimer’s and Light at Night: Taking action to prevent this disease
Light at night and the link to Alzheimer’s disease. Animal studies show that disrupting circadian rhythm with light at night causes an increase in amyloid plaque accumulation.