Prions: When proteins go awry
Prions are able to infect, causing the normal protein around them to also misfold. These misfolded proteins aggregate to cause neurogenerative disease. Susceptibility to prion diseases depends in part on your genes.
Alzheimer’s
Serotonin 2A receptor: Psychedelic response and Alzheimer’s disease
Learn how new research on brain aging and dementia connects the serotonin 2A receptor with psychedelics, brain aging, and Alzheimer’s.
TREM2 and Alzheimer’s Disease Risk
The TREM2 gene is important in how the brain’s immune system functions. Learn how variants in this gene impact the risk for Alzheimer’s disease.
SOD1 Gene: Your Antioxidant Defense System
Our body has built-in antioxidants that fight against cellular stress. The superoxide dismutase enzyme fights against oxidative stress in your cells.
Lithium Orotate: Mood, Alzheimer’s, and Aging
Researchers found that Texas counties with higher levels of lithium in their groundwater had less of an increase in Alzheimer’s rates compared with counties that had lower levels of lithium. This isn’t a total surprise since previous studies had linked lithium to a decreased risk of dementia, but it is a great confirmation at a large scale population level.
A Klotho Gene Variant Reduces Alzheimer’s Risk for APOE E4 Carriers
The Klotho protein is involved in many of the diseases of aging. Learn more about this gene and find out how your Klotho variants may impact healthy aging.
Alzheimer’s Genes: APOE
The APOE gene variants are tightly linked with the risk of Alzheimer’s disease. Find out whether you carry the APOE risk type for Alzheimer’s – and learn what all of us can do via diet and lifestyle to prevent this disease.
Genetic Mutations that Protect Against Alzheimer’s Disease
Just like there are genetic variants that increase the risk of Alzheimer’s, there are also variants that protect against this disease. Check your genetic data to get a better picture of your risk factors. (Member’s article)
Melatonin receptor gene: Alzheimer’s risk and night shift work
Shift work and ‘social jet lag’ are linked to an increased risk for several chronic diseases. A genetic variant in the MTNR1A gene impacts melatonin receptors in the brain. (Member’s article)
Alzheimer’s and Light at Night: Taking action to prevent this disease
Too much blue light at night is standing out as a player in circadian rhythm dysfunction and can increase your risk of Alzheimer’s disease. Discover ways to improve your sleep quality and environment to help lower your modifiable risk.