Norepinephrine: Focus, stress, genetics, and brain function
Discover how norepinephrine and your genes affect ADHD, ME/CFS, long COVID, POTS, and mood, plus evidence‑based ways to support healthy norepinephrine balance.
Disease Prevention
Your genes interact with your diet and lifestyle to influence your susceptibility to diseases. You can use your genetic data here in a couple of ways:
- Find the root cause: If you are dealing with a health condition, learn how to use your genetic data to get to the right solutions.
- Be proactive: Find out what you are genetically more susceptible to and what to do to prevent it.
Where to start in Disease Prevention?
- Top 10 Genes to Check
- Migraines: Genetics, causes, and pathways to target
- Specialized Pro-resolving Mediators and Resolving Chronic Inflammation
- Pancreatitis and Exocrine Pancreatic Insufficiency
Members: Check out the Disease Prevention Topic Summary Report for a quick overview of all your genetic variants related to disease prevention.
Articles and Genotype Reports ▼
TRPM3: The Ion Channel Behind Pain, Migraines, and ME/CFS
TRPM3 is a calcium ion channel involved in heat sensing, pain transmission, migraines, and immune function. Your TRPM3 gene variants may affect susceptibility to ME/CFS, long Covid, and chronic pain.
Gut Mucosal Barrier & Mucin Genes: Diet and DNA Shape Your Gut Defense
Your gut mucosa protects you from microbes in the gut, your own digestive enzymes, and toxins from the environment. Learn what you can do to keep your gut mucosal barrier healthy.
BChE gene: Nightshade sensitivity, Anesthesia risk
Genetic variants of the BChE gene decrease its enzyme’s activity. This can lead to various and seemingly unconnected consequences…such as an increased risk for Parkinson’s or food sensitivity to potatoes.
Trigger Points, Myofascial Pain Syndrome, and Underlying Causes
Trigger points are hyperirritated knots in the muscle and fascia that can refer pain to a nearby region of the body.
Risk of Osteonecrosis from Bisphophonates
A small percentage of people taking bisphosphonates will experience osteonecrosis – bone death – in the jaw. Genetic variants are part of the susceptibility.
Dry Eyes: Using Genetic Data to Find the Right Solutions
Use your genetic data to understand the root causes of dry eyes, from immune response to meibomian glands, and explore research-backed options to relieve symptoms.
Polycythemia Vera: Understanding Inherited and Somatic Mutations behind This Rare Blood Disorder
Polycythemia vera: See how your genetics and environment contribute to this rare blood disorder. Understand the causes, risks, and role of inheritance.
Your APOE Type and Alzheimer’s Risk: How to Find It, What It Means, and What to Do
Find out your APOE type, understand your Alzheimer’s risk by genotype, sex, and ancestry, and learn about real prevention strategies.
Carnitine: Genetic Variants Affecting Mitochondrial Energy and Health
Learn how carnitine powers cellular energy, supports organ health, and influences metabolism. Discover its benefits for brain, liver and immune function, plus how genetics affect your carnitine needs.
FTO and m6A Methylation
Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
Building Up Iron: Hemochromatosis Mutations
A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.
PCSK9: Cancer Recurrence & Prevention
Lower PCSK9 levels have been shown in research studies to correlate to a significantly reduced risk of metastatic recurrence in certain types of cancer.
Pyruvate Dehydrogenase Deficiency – Mitochondrial Dysfunction and Lactate Production
Pyruvate Dehydrogenase is central to cellular energy production. Learn about its role in energy production, genetic mutations, association with ME/CFS and Long Covid, and strategies to manage its deficiencies.
Aspirin, Colon Cancer Prevention, and Genetics
For some people with specific genetic variants, aspirin may help to prevent colon cancer. Learn more about what the research says and check your genes.
Prostate Health: How Genes, Diet, and Lifestyle Shape Your Risk
Do you know someone that suffers from prostate problems? Learn more about this important gland and how your genes affect your risk.
Parkinson’s Disease Risk: Genetics, Environmental Exposures, and Prevention Strategies
Parkinson’s: Explore key genes, environmental risks, gut microbiome factors, and research‑based lifehacks that may help protect dopaminergic neurons.
Gilbert’s Syndrome: A Genetic Disorder Causing High Bilirubin
Gilbert’s syndrome is an inherited condition where the body doesn’t break down bilirubin efficiently. Discover the benefits of higher bilirubin levels in this syndrome and some possible risks.
BH4: Tetrahydrobiopterin Synthesis, Recycling, and Genetic SNPs
Tetrahydrobiopterin (BH4) is an essential cofactor in the production of neurotransmitters and nitric oxide. Genetic variants impact BH4 levels which can affect heart disease, cognitive function, and immune response.
Fibronectin, Genetics, and Alzheimer’s Prevention
Genetic variants in FN1 that reduce fibronectin also protect against Alzheimer’s in people with APOE E4. Here’s how to check your genes.
BRCA1 and BRCA2 Mutations: Interactions with Environment, other Genetic Variants
Women with BRCA1/2 mutations may face additional risk from certain environmental toxins or other genetic variants.
Back Pain: Genetics, Root Causes, and Solutions
For some people, back pain is a daily occurrence that drastically affects their quality of life. For others, it may be an intermittent nagging problem, often without rhyme or reason. Your genes play a role in whether disc degeneration gives you back pain.
Top 11 Genes to Check in Your Genetic Raw Data
Wondering what is important in your raw genetic data? Check out this list of 10 genes in your 23andMe or AncestryDNA data.
Fragile X Syndrome
Fragile X Syndrome is a genetic disorder that can cause changes in a person’s ability to learn and causes alterations in behavior. It is caused by mutations in the FMR1 gene.
Wilson’s disease: ATP7B Gene Mutations and Copper Accumulation in the Brain
Mutations in ATP7B can cause copper dysregulation and Wilson’s disease. People carrying one copy of the mutation may also have subtle changes.