Gut Mucosal Barrier: Foundational and Underappreciated
Your gut mucosa protects you from microbes in the gut, your own digestive enzymes, and toxins from the environment. Learn what you can do to keep your gut mucosal barrier healthy.
Gut Health
Your genes interact with your gut microbiome and your gut microbiome impacts your overall health.
Find out how your genes impact which bacteria can live in your gut and which foods are likely to be a problem for leaky gut.
Where to start?
- Leaky Gut, Genetics, and Processed Foods
- Genetic reasons a low FODMAPs diet doesn’t work
- FUT2: Non-secretors and the gut microbiome
Members: Check out the Gut Health Topic Summary Report for a quick overview of all your genetic variants related to the function of your gut.
Latest articles about Gut Health:
Histamine Intolerance: Genetic Report, Supplements, and Real Solutions
Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance.
Leaky Gut Genes: Emulsifiers in Processed Foods
Emulsifiers, found in many processed and packaged foods, can trigger an inflammatory response in the intestines based on whether you carry specific genetic variants.
Fatty Liver: Genes that increase the risk of NAFLD
Non-alcoholic fatty liver disease (NAFLD) can be caused by genetic susceptibility, diet, and lifestyle factors. The good news is that fatty liver disease is reversible.
Celiac Genes: How to Check Your Raw Data
Celiac disease is caused by a combination of environmental factors (eating gluten, other factors) and having the genetic variants that cause susceptibility to the disease. Without the genetic susceptibility, you won’t have celiac.
Genetic Reasons Why Low FODMAPs Isn’t Working For You (SI Gene)
The low FODMAPs diet is often recommended as a starting point for anyone with IBS symptoms but genetics can limit its effectiveness.
Is IBS genetic? Targeted Solutions, Based on Your Genes
There are multiple causes of irritable bowel syndrome (IBS), and genetics can definitely play a role in IBS symptoms. Pinpointing your genetic cause may help you to figure out the right solution for you. (Member’s article)
FUT2: Check to See if You Are a Secretor or Non-Secretor
A genetic variant in the FUT2 gene controls whether or not you secrete your blood type into your saliva and other bodily fluids, such as your intestinal mucosa. This alters the gut microbiome – and protects you from Norovirus.
Gut Genes: How your genetic variants impact your gut microbiome
This article digs into how the genetic variants you inherited from mom and dad influence the bacteria that can reside within you and how dietary changes can make a difference.
Mushroom intolerance: Ergothioneine and the OCTN1 gene
Mushrooms contain a healthy antioxidant called ergothioneine. But for people with a SLC22A4 genetic variant, this antioxidant can be too much of a good thing, leading to intestinal problems. Check your genetic data to see if you carry this mushroom intolerance variant.
Does eating meat put you at a higher risk for colon cancer?
Depending on their processed meat intake, people who carry certain genetic variants are at an increased risk for colon cancer. You can check your genetic data to see if processed meat will likely increase colon cancer risk.
How your genes shape your gut microbiome and weight
Differences in our microbiome might shape how we gain weight. Here’s a look at a few of the genes that play a role in determining which microbes inhabit the gut microbiome.
Digesting Carbohydrates: Amylase variants
Carbohydrate digestion begins in the mouth with an enzyme called amylase. Take a look into how the amylase enzyme works, genetic variants that impact your production of amylase, and solutions if you are low in amylase.
Inflammatory Bowel Disease, Genes, and Gut Microbes
All of the general advice, fix your gut, eat more fiber, eat fermented foods, avoid sugar, grains, dairy, etc., may work for some but not for everyone. Take a good look at some of the genes that affect our microbiome.
Leveraging your gut microbiome to change your gene expression
Learn how your gut microbiome influences the expression of your core circadian rhythm genes.
Gut Health Topic Summary Report
Utilize our Gut Health Topic Summary Reports with your 23andMe or AncestryDNA genetic data to see which articles may be most relevant to you. These summaries are attempting to distill the complex information down into just a few words. Please see the linked articles for details and complete references. (Member’s article)