Is IBS genetic? Targeted solutions, based on your genes

There are multiple causes of irritable bowel syndrome (IBS), and genetics can definitely play a role in IBS symptoms. Pinpointing your genetic cause may help you to figure out the right solution for you. (Member’s article)

Histamine Intolerance and Your Genes

Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance. Knowing which genetic variants you carry leads to targeted solutions that are more likely to work for you.

Gut Genes

This article digs into how the genetic variants you inherited from mom and dad influence the bacteria that can reside within you and how dietary changes can make a difference.

Gut Health Topic Summary Report

Utilize our Gut Health Topic Summary Reports with your 23andMe or AncestryDNA genetic data to see which articles may be most relevant to you. These summaries are attempting to distill the complex information down into just a few words. Please see the linked articles for details and complete references. (Member’s article)

How to check your genetic raw data for celiac genes

Celiac disease is caused by a combination of environmental factors (eating gluten, other factors) and having the genetic variants that cause susceptibility to the disease. Without the genetic susceptibility, you won’t have celiac.

conversion of tryptophan to kynurenine or serotonin

Tryptophan Genes: Serotonin, Melatonin, and Kynurenine

Tryptophan is an amino acid that the body uses to make serotonin and melatonin. Genetic variants can impact the amount of tryptophan that is used for serotonin. This can influence mood, sleep, neurotransmitters, and immune response.

Digesting Carbohydrates: Amylase variants

Carbohydrate digestion begins in the mouth with an enzyme called amylase. Take a look into how the amylase enzyme works, genetic variants that impact your production of amylase, and solutions if you are low in amylase. (Member’s article)

Mushroom intolerance genes

Mushroom intolerance: Ergothioneine and the OCTN1 gene

Mushrooms contain a healthy antioxidant called ergothioneine. But for people with a SLC22A4 genetic variant, this antioxidant can be too much of a good thing, leading to intestinal problems. Check your genetic data to see if you carry this mushroom intolerance variant.

How our genes shape our gut microbiome and our weight

Differences in our microbiome might shape how we gain weight. Several studies have come out recently showing that those who are overweight have a different gut microbiome composition than those who are lean. Here’s a look at a few of the genes that play a role in determining which microbes inhabit the gut microbiome.