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Can you get the COVID vaccine if you have MTHFR?

I’ve recently seen several questions about MTHFR and the COVID vaccines. A lot of people wonder if carrying the MTHFR mutation is a reason not to get vaccinated.

Let me give you the quick answer: There is no research showing that the MTHFR genetic variant is a reason not to get vaccinated.

In fact, going back through a couple of decades of research on MTHFR and vaccines leads to only one study showing a negative link. This study was on a vaccine for smallpox — one that is not normally given anymore. It really doesn’t apply to current vaccines.[ref]

Read more about MTHFR and Vaccine research studies

COVID-19 has been the subject of several genetic studies to determine which genes are related to severity. There is no connection between MTHFR genetic variants and COVID-19 severity.

Read more about Genetics and COVID.

What does the research show on MTHFR? Check out the full article on Methylation and MTHFR with links to how to check your genetic raw data.


About the Author:
Debbie Moon is a biologist, engineer, author, and the founder of Genetic Lifehacks where she has helped thousands of members understand how to apply genetics to their diet, lifestyle, and health decisions. With more than 10 years of experience translating complex genetic research into practical health strategies, Debbie holds a BS in engineering from Colorado School of Mines and an MSc in biological sciences from Clemson University. She combines an engineering mindset with a biological systems approach to explain how genetic differences impact your optimal health.