Genetics plays a huge role in your immune response — from how you fight off diseases to chronically increased inflammation.
Learn how to use your genetic data to target chronic inflammation, and find out how important your genes are in which bacteria and viruses you are likely to be susceptible to.
Looking for information on an autoimmune disease? Check out these articles.
Do you know of someone with unexplained heart palpitations, spiking blood pressure, dizziness, and tinnitus? Discover how research is linking these symptoms to histamine, mast cells, and the spike protein.
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Chronic inflammation is at the root of all diseases. New research discusses how pro-resolving mediators are the key to the resolution of inflammation.
Alopecia areata is an autoimmune-like disorder in which the immune system attacks the hair follicle. Learn about the triggers of alopecia areata, why the hair falls out, genetic variants that increase susceptibility, and possible treatment options.
The CCR5 gene is an important player in the immune response. A mutation in the CCR5 gene, called the Delta32 mutation, significantly reduces the chance of an HIV infection.
Are you always tired even when you know you slept well? Discover more about the newest research on fatigue and how genetic susceptibility plays a part for some people.
Learn why zinc is important for your immune system and so much more. Find out how your genes impact your need for zinc and discover ways of boosting your zinc status.
Genetics plays a role in the susceptibility to antibiotic allergies. Learn which genetic variants increase your risk.
Your genes play a role in your susceptibility to migraines. Find out what is going on when you have a migraine and solutions that fit your genes.
Will you get side effects from mRNA vaccines? A genetic variant in the HLA-A gene might cause an increase in your response to the vaccine.
In recent research, mutations in TLR7 (a sensor in our innate immune system) might cause severe Covid-19 in a small minority of healthy people.
Interested in low histamine foods and recipes? This article focuses on foods high in histamine so you can easily eliminate them from your diet.
What makes people more susceptible to inflammatory chronic diseases? The root of the over-activation of inflammation for some people could be the NLRP3 inflammasome.
Do you have a food allergy? Discover how environmental factors and genetic susceptibility can shape individual reactions.
A lot of people use the MTHFR variants as a reason not to vaccinate their kids. Is there any science to back this up? See what the research says.
Not everyone gets sick when exposed to the SARS-CoV-2 virus. While there are many factors that come into play here, research points to genetics as playing a role. Several good genetic studies have recently been released showing which genes are important in COVID-19 susceptibility. Learn more and check your genes.
Genetic Variants involving the ADAMTS13 gene and VWF (von Willebrand Factor) can increase the risk of blood clots and thrombocytopenia.
A look into the role of platelets, their connection to blood clots, and a discussion of the research on adenovirus-vector therapy, thrombocytopenia, and platelet reactions.
Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance. Knowing which genetic variants you carry leads to targeted solutions that are more likely to work for you.
People who carry the genetic mutations that cause G6PD deficiency are at an increased risk for hemolytic anemia when taking quinine-based medications. This article is intended to be a ‘heads up’ for anyone who is considering using quinine or chloroquine without a doctor’s advice for COVID-19.
Discover why inflammation causes depression and how your genetic variants in inflammatory genes may play a role in depression or anxiety.
A genetic variant in the FUT2 gene controls whether or not you secrete your blood type into your saliva and other bodily fluids, such as your intestinal mucosa. This alters the gut microbiome – and protects you from Norovirus.
A look into the science of the lingering effects triggered by viruses including chronic fatigue syndrome and long-haul viruses.
Do you feel like you are always dealing with inflammation? Joint pain, food sensitivity, etc? Perhaps you are genetically geared towards a higher inflammatory response. Tumor necrosis factor (TNF) is an inflammatory cytokine that acts as a signaling molecule in our immune system.
Utilize our Immune and Inflammation Topic Summary Reports with your 23andMe or AncestryDNA genetic data to discover the articles most relevant to you. These summaries distill the complex information down into just a few words. Please refer to the linked articles for details and complete references. (Member’s article)
The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.