Getting Started FAQs
How do I look up a SNP (rs id) on 23andMe?
23andMe allows you to browse your raw data from your account.Log in to your 23andMe account and click on your name in the upper right corner. In the dropdown, choose “Browse Raw Data”. After selecting the ‘Browse Raw Data’ option, you can type the SNP rs id information into the search bar. The information shown will include your genotype for that specific sequence. We also recommend that you download your raw data and store it safely. How to download your 23andMe Raw Data.
How do I look up a SNP (rs id) in AncestryDNA data?
You must download your raw data file from AncestryDNA before you can look up an SNP. Once downloaded and unzipped, it will be a text file. While you can search a text file for the specific data, it is easiest for future searches to go ahead in import it into an Excel file. Once in Excel, you can search your data using the Find command in Excel. If you need specific step-by-step instructions, please read over How to download your AncestryDNA raw data.
What do the different version numbers mean?
Beside each rs id in Genetic Lifehacks articles, you will see in parentheses whether the information is available in 23andMe or AncestryDNA raw data.
For 23andMe, the version of the raw data file indicates when that version was in service. When a new version releases, the company changes some gene sequences. This means each version has a possibly different set of sequenced genes from the previous version. V4 data ranges from 2014 to mid-2017 and V5 data started mid-2017 and is the present version. Most of the rs ids that are marked as V4 will also be available in V3 data.
What is a genotype?
Genes are made up of DNA and are the basic units of heredity. A collection of genes in the genome becomes an organism’s genotype.
Can genes change over time?
Yes and no – but mainly no.
DNA is made of nucleotide bases (A), guanine (G), cytosine (C), and thymine (T). The nucleotide bases (letters) in our DNA sequence do not change. Genes are made of DNA.
Your nuclear DNA gets copied each time a cell replicates. There is a possibility for an error to occur in the replication, causing a mutation in the replicated cells. (Mutations in oncogenes are how cancer occurs.)
In general, though, your genes are what you were born with. While your DNA doesn’t change (much) since conception, see the epigenetics question below for information on how the genes are turned on or off.
What is epigenetics?
Epigenetics is the study of biological systems that cause genes to turn on and off. Biological systems affect how cells read genes and then ‘when or if’ proteins are made. Genes shouldn’t remain on all of the time. Regulation is important for certain signals to turn them either on or off.
Can I influence the way my genes turn on and off?
How you live your life is the biggest modifier to turning on and off genes. What you eat, how you exercise, how you sleep, where you live, how you interact with people all influence chemical changes in your body that influence how your cells read the genes. These chemical changes then go on to influence how genes turn on and off.
Can I modify my risk to certain diseases?
Absolutely! A healthy lifestyle and environmental changes affect and influence how your genes express (how they turn on and off). These changes can reduce disease risk if you are genetically predisposed. Everyone knows that they should eat healthy meals, be active, keep stress levels low, and avoid smoking for disease prevention. But there is more to the living healthy puzzle. We include a section called Lifehacks in each of our articles. These ‘hacks’ include evidence-based solutions to apply, based on your genes. By including current health and genetics research, you can fine-tune your supplements or lifestyle changes to improve your quality of life.
Privacy and Ethics on Genetic Lifehacks
Why aren’t there any ads on Genetic Lifehacks?
Allowing ads on our site comes with an unwanted price to your privacy. Ads track your data. The data is valuable because it shows if you purchased a product, signed up for a newsletter, or contacted a business to name a few actions. The business of data is very profitable and ubiquitous with just about every company online. We didn’t want that for our members.
Will you sell your member data?
No and never. Genetic Lifehacks stores no personally identifiable information from your use of this website, except in the case of ordering a product. When you order a report or membership, the use of your order information helps provide that service to you. For example, we keep your email address and provided name so you can log in to the membership section of the website. Genetic information will only be used to provide you information for the consultation or reports and will not be shared, sold, used for research, or stored long term. Your genetic data will not be used to sell you products. Because your genetic data is not being stored, Genetic Lifehacks cannot sell your data as a company asset.
What does it mean when my genotype is – -?
There are a couple of reasons why you might find the dashes for your genotype. The first being you haven’t uploaded your genetic text file to the browser. This must happen every time you want to access the articles with your genotypes. We have a great tutorial video here with printable instructions. Please note, if you don’t clear your data after each use, it will remain in your browser’s temporary files cache until you do. The second reason would be you don’t have that version for 23andme. If it is for only v5 data and you have 23andme’s v4, you will get the dashes…and visa versa.
I have data from more than one genetics provider. Can I use it?
If the data is in the .txt format of 23andMe or AncestryDNA, it will work with the membership features. Simply disconnect from one data file by clicking the ‘clear data’ button and then connect to the other data file.
If you have both AncestryDNA and 23andMe data, you can combine the two files into one. We have instructions on the process here.
How do I cancel my monthly membership?
While we hate to see you go, it is easy to cancel your subscription. Just log in and go to the member’s account information page. Click on Subscription to manage or cancel your subscription.