Depression Causes: Genetic Overview
Depression can have multiple physiological causes. This article ties together 9 separate articles on depression to simply your genetic search.
Mood and Brain
Your genes make you unique! From mood to cognitive function, your genetic variants interact with your lifestyle and environment to impact your risk of mood disorders.
Learn how to work with your genetic variants to optimize cognitive function and improve mood issues.
Please keep in mind that these articles for educational purposes — learn about the biochemistry, understand your genetics, and talk with your doctor if you have medical questions.
Member’s: Check out the Brain and Mood Topic Summary Report for a quick overview of all your genetic variants related to mood and cognitive function.
ANK3: Bipolar Disorder and Brain Development
The genetic variants in the ANK3 gene impact the risk of psychiatric disorders that include bipolar disorder and autism spectrum disorders, and heart arrhythmia. Discover how ANK3 impacts neuronal formation and transmission and how this ties into an increased risk of psychiatric disorders.
Psychopath Genes: Born not made?
Can you be born a psychopath? Are there genes linked to psychopathy? Discover how your genes don’t predestine you to become a psychopath.
VMAT2 gene: The God Gene and Neurotransmitters
An examination on the current research for the ‘God gene’, explaining what it does and its importance in Parkinson’s disease.
Nootropics and Genetics: Best Smart Drugs with Your Genes (2021)
Nootropics are supplements used to boost cognition and memory. Learn how the substance works and the genes connected to the mechanism of action.
Depression, genetics, and mitochondrial function
How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.
Serotonin: How your genes affect this neurotransmitter
Serotonin is a neurotransmitter that is important in depression, sleep, and many other aspects of health. Learn how your genetic variants in the serotonin receptor genes impact their function.
COMT: Interactions with Supplement
Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.
Serotonin 2A receptor variants: psychedelics, brain aging, and Alzheimer’s disease
Learn how new research on brain aging and dementia connects the serotonin 2A receptor with psychedelics, brain aging,and Alzheimer’s.
Is Anxiety Genetic?
This article covers genetic variants related to anxiety disorders. Genetic variants combine with environmental factors (nutrition, sleep, relationships, etc), when it comes to anxiety. There is not a single “anxiety gene”. Instead, there are many genes that can be involved – and many genetic pathways to target for solutions.
Is inflammation causing your depression and anxiety? Inflammation genes and mood
Discover why inflammation causes depression and how your genetic variants in inflammatory genes may play a role in depression or anxiety.
CBD Oil: Genes and Receptors
Why do some people get such great benefits from CBD while others notice nothing? It is likely that your genes play a role in how your body responds to CBD. This article covers the research studies on CBD, the receptors that CBD binds to, and how your genetic variants could be influencing your response (or lack thereof) to CBD oil. (Member’s article)
Lithium Orotate, Vitamin B12, and Mood
For some people, low-dose, supplemental lithium orotate is a game changer when combined with vitamin B12. But other people may have little to no response. The difference may be in your genes.
Depression, Genetics, and Circadian Rhythm
For some people, circadian disruption can be chronic – and at the heart of depression or mood disorders. Genetic variants play a role in this susceptibility. Fortunately, there are solutions that may help.
Tryptophan Genes: Serotonin, Melatonin, and Kynurenine
Tryptophan is an amino acid that the body uses to make serotonin and melatonin. Genetic variants can impact the amount of tryptophan that is used for serotonin. This can influence mood, sleep, neurotransmitters, and immune response.
GABA levels: Genetic variants that impact this inhibitory neurotransmitter
GABA (gamma-Aminobuyteric acid) is a neurotransmitter that acts to block or inhibit a neuron from firing. It is an essential way that the brain regulates impulses, and low GABA levels are linked with several conditions including anxiety and PTSD. (Member’s article)