Lactate, Lactate Dehydrogenase, and Lactate Transporters
Lactate is much more than a workout byproduct—it’s a key energy source, signaling molecule, and regulator of metabolism, brain health, and disease.
Brain and Mood
Smarter, Happier, and Focused…
Unlock the potential of your mind by understanding how your genes impact the production of neurotransmitters. Learn how to optimize your diet and lifestyle for mood, focus, and cognitive abilities.
Why Neurotransmitters Matter
Neurotransmitters are the chemical messengers of your brain, playing crucial roles in:
- Regulating mood and emotions
- Enhancing cognitive function and focus
- Managing stress and anxiety
- Improving sleep quality
Where to start?
- ADHD: Understand your genetics, environment, and neurochemistry
- Mood: Lithium orotate and Vitamin B12
- Depression: Dive deep into root causes and genetic pathways
- Anxiety: Genetic factors and pathways for treatment
Members: Start with the Brain and Mood Topic Summary Report for a quick visual way to know which articles to read first.
Latest articles about Mood and Brain:
Reelin – Long Covid, Depression, and Alzheimer’s
Reelin is a key glycoprotein involved in brain development, cognition, and neurodegenerative diseases like Alzheimer’s, schizophrenia, autism, and cardiovascular health.
Glutamate Receptors and Transporters
Glutamate transporters and receptors carefully balance glutamate levels in the brain. Variants in the glutamate genes can affect how your brain balances glutamate.
Opioid Receptors Genetic Variants and Addiction
Genetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction. (Member’s article)
Neuropilins: Neurodevelopmental Disorders, Gut Barrier, & Covid Brain
Neuropilins act as receptors and are found on the surface of cells. Learn about its many roles body, such as in the immune, vascular and nervous systems.
OCD: Obsessive-Compulsive Disorder Genes
Genetic variants play a role in susceptibility to obsessive-compulsive disorder. Understanding your genes may help you understand OCD better and help you to target the right treatment.
HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions
Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
ADHD: Causes, Neurochemistry, and How to Check Your Genetic Raw Data
Discover the complex interplay of genetics and environment in ADHD susceptibility. Learn how circadian rhythm and neurotransmitter genes contribute to the disorder, and how toxicant exposure may increase risk.
Brain Fog: Causes, genetics, and individualized solutions
Explore brain fog in detail, looking at the physiological causes, genetic susceptibility, and personalized solutions.
Schizophrenia: Genetic and Environmental Factors
Schizophrenia is a complex disease caused by a combination of genetic susceptibility along with environmental factors. Research points to multiple pathways involved in schizophrenia and schizoaffective disorder.
Highly Sensitive People: Genes, Brain Function, and Sensory Sensitivity
Genetic variants are linked to being a Highly Sensitive Person – feeling more deeply and more sensitive to environmental stimuli.
MAO-A and MAO-B: Neurotransmitter levels, genetics, and warrior gene studies
The MAOA and MAOB genes encode enzymes that break down certain neurotransmitters. People with low MAO may be prone to mood issues in certain circumstances.
Glutamate: Synthesis, transport, and supplement interactions
Glutamate is synthesized from glutamine or alpha-ketoglutarate. Imbalanced glutamate levels play a role in several neurological disorders.
Dopamine Synthesis SNPs: Genes, lifestyle, diet, and dopamine optimization
Two key enzymes are needed for dopamine synthesis. Genetics, diet, and lifestyle can influence your dopamine production.
Creatine: Boosting Muscles and Increasing Brain Power
Creatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.
Plasmalogens: Healthy Brain Aging and More
Plasmalogen levels in the brain are key to brain health. Low plasmalogen is linked to Alzheimer’s and ME/CFS. Healthy ways to boost your levels.
Migraines: Genes, Root Causes, and Personalized Solutions
Your genes play a role in your susceptibility to migraines. Find out what is going on when you have a migraine and solutions that fit your genes.
Statins and Brain Fog: Exploring how statins impact memory and cognitive function
Understand the connection between statin use and brain fog. Dive into the research on how cholesterol-lowering drugs impact cognitive health and memory.
Dopamine Receptor SNPs: Addiction, Mood, ADHD, and Schizophrenia
Dopamine is a powerful player in our cognitive function – impacting mood, movement, and motivation. Genetic variants in the dopamine receptors influence addiction, ADHD, neurological diseases, depression, psychosis, and aggression.
Lithium Orotate and Vitamin B12: Benefits for Mood and Cognitive Support
For some people, low-dose, supplemental lithium orotate is a game changer when combined with vitamin B12. But other people may have little to no response. The difference may be in your genes.
Is Inflammation Causing Your Depression and Anxiety? The Science Behind the Link
Discover why inflammation causes depression and how your genetic variants in inflammatory genes may play a role in depression or anxiety.
Dyslexia: Genes + Early Life Stressors
While dyslexia is known to run in families, the role of genetics in dyslexia is still being determined. Here is a quick look at some of the genes involved in dyslexia, affecting around 10% of the population.
COMT: How to Optimize Your Supplements for Your COMT Genotype
Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.
Anxiety: Genetics, heredity, and personalized solutions
When it comes to anxiety, genetic variants combine with environmental factors (nutrition, sleep, relationships, etc) when it comes to anxiety. Understanding your anxiety genes can help you figure out which pathways to target.
Alcohol Addiction: Exploring the Genetic and Environmental Factors
Discover the role of genetics, stress, and neurotransmitters in alcohol use disorder. Alcohol dependence is complex; understand your genes and the research on treatment options.