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Mercury Detoxification: Genomics and Solutions

Mercury Detoxification: Genomics and Solutions

What are the physiological effects of mercury and how does the body eliminates it? Discover how genetic variants play a role in how quickly you excrete mercury.

Alpha-1 Antitrypsin Deficiency, SERPINA gene variants that lead to A1AT deficiency

Alpha-1 Antitrypsin Deficiency: Genetic Raw Data, Carrier Effects, Interactions with TNF

A genetic mutation in the SERPINA1 gene causes alpha-1 antitrypsin deficiency. This increases a person’s susceptibility to COPD (chronic obstructive pulmonary disease) and, in some cases, cirrhosis of the liver. Knowing that you carry this mutation can be a great incentive to avoid smoking and to be kind to your liver.

GSTM1: GST enzymes and glutathione for environmental toxins, GST genetic variants, Phase II detoxification

GSTM1: GST Enzymes and Glutathione for Environmental Toxins

Exposure to many different man-made chemical compounds occurs every day, and our exposure to new toxicants exceeds what our ancestors experienced. Several common GST variants decrease the function of the GST enzymes.