Familial Mediterranean fever (FMF) is a genetic condition of inflammatory episodes that cause painful joints, pain in the abdomen, or pain in the chest. It is most often accompanied by a fever. FMF is often misdiagnosed as various pain-related conditions such as fibromyalgia, myofascial pain syndrome, or gouty arthritis.
Explore brain fog in detail, looking at the physiological causes, genetic susceptibility, and personalized solutions.
Do your fingertips turn white and blue when cold? Discover the causes and symptoms of Raynaud’s syndrome and your genetic susceptibility.
In recent research, mutations in TLR7 (a sensor in our innate immune system) might cause severe Covid-19 in a small minority of healthy people.
A look into the research-backed studies showing how certain vaccines may slightly increase the absolute risk of autoimmune diseases in susceptible individuals. (Member’s article)
The PTPN22 gene plays a pivotal role in that balance, and genetic variants (SNPs) in PTPN22 increase your risk of autoimmune conditions such as vitiligo, alopecia, RA, type 1 diabetes, and autoimmune thyroid diseases. (Member’s article)
The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.
Lupus is a complex autoimmune disease that can impact several different systems in your body. Learn more about how your genetic variants impact the “why” for this autoimmune disease.