Understanding Parkinson’s Disease: Genetic Susceptibility and Environmental Triggers
Discover how genetic variants and environmental factors combine to increase Parkinson’s disease risk. Learn about key genes, toxins, and prevention insights.
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Trimethylaminuria: FMO3 mutations that cause malodorous body odor
Often referred to as ‘fish odor disease’, trimethylaminuria causes a strong odor in sweat, urine, and breath. This article explores the FMO3 gene, which encodes the enzyme that breaks down trimethylamine.
HMGB1 gene: inflammatory response protein important in sepsis and COVID-19
The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.
CYP2A6: Breaking down nicotine and other medications
How many cigarettes a day a person smokes – and how hard it is for them to quit – is at least partly dependent on the CYP2A6 gene. This enzyme also metabolizes several important cancer drugs.