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How mast cells release histamine and other mediators in mast cell activation syndrome, and the genetics that influence MCAS

Mast Cells: MCAS, Genetics, and Solutions

Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.

Genetic variants that affect Heat Shock Proteins Reasons to upregulate and downregulate heat shock proteins

Heat Shock Proteins: Cellular Resilience

Heat shock proteins are activated by cells in response to a stressful condition, such as exposure to high heat. Learn more about the essentials of heat shock proteins, including how to activate them and the genetic variants that impact how well they work.