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IL-2 Genetics and Immune Balance

IL-2 Genetics and Immune Balance

IL-2 dysregulation affects long COVID, autoimmune diseases, and cancer therapy response. Learn about your IL-2 genetic variants and natural ways to support IL-2.

Illustration of the NLRP3 inflammasome and the chronic inflammation it drives

NLRP3: Genetic Variants that Increase Chronic Inflammation

Explore NLRP3 inflammasome genetics: How variants drive chronic inflammation in Alzheimer’s, diabetes, and autoimmune diseases. Discover triggers, health risks, and lifehacks like zinc & vitamin D to modulate it.

How IL-13 shifts the immune system toward a Th2 response, raising asthma and eczema risk

IL-13: Elevating Th2 Immune Response and Asthma risk

Interleukin-13 (IL-13) is a signaling molecule important in the immune response. Excessive IL-13 can tip you toward a Th2-dominant immune response, and variants increase the risk of allergies and asthma.

HMGB1: From Nuclear Organizer to Inflammatory Alarmin

HMGB1 gene: inflammatory response protein important in sepsis and COVID-19

The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.