This group gathers articles on conditions like chronic pain, fatigue, and other neurological or musculoskeletal issues with genetic contributions.
TRPM3 is a calcium ion channel involved in heat sensing, pain transmission, migraines, and immune function. Your TRPM3 gene variants may affect susceptibility to ME/CFS, long Covid, and chronic pain.
Genetic variants in immune, mitochondrial, and inflammatory pathways (NK cells, NLRP3, interferon, complement, TRP channels) increase ME/CFS susceptibility. Check your genes and explore research-backed solutions.
Trigger points are hyperirritated knots in the muscle and fascia that can refer pain to a nearby region of the body.
Explore the genetic basis of POTS, from HLA and norepinephrine transporter variants to EDS, MCAS, and long Covid connections, plus strategies to better manage symptoms.
Discover how genetics, triggers, and personalized strategies shape migraine prevention and relief. Find actionable solutions based on your DNA.
Learn about the potential causes of fibromyalgia, including inflammation, genetics, and hypersensitivity to pain, along with overlapping conditions that complicate diagnosis.
Inflammation and breakdown of cartilage are at the root of osteoarthritis. Learn how your genes impact the pathways involved in arthritis.
Genetic polymorphisms in COMT affect how we feel certain types of pain. These variants are linked to increased susceptibility to chronic pain disorders.
Are you always tired even when you know you slept well? Discover more about the newest research on fatigue and how genetic susceptibility plays a part for some people.
Have you tried acupuncture? This treatment has been around for thousands of years but did you know that your genetic variants can impact how well you respond?
Do you have problems with your tennis elbow, rotator cuff, knees, or Achilles tendon? Discover how your genes influence the risk of having tendon problems.
Small Fiber Neuropathy (SFN) results in burning pain, numbness, odd sensations, or autonomic nervous system issues. Learn more about the possible causes and potential solutions to this debilitating disorder.
Inclusion body myositis is a progressive, chronic condition that causes muscle weakness. It may be an interplay between inflammation, the dysregulation of proteins, mitochondrial dysfunction, and changes to autophagy. Somewhere in the mix, autoimmunity may be triggering it.
Genetics plays a role in both Meniere’s disease and tinnitus. Understanding your genetic susceptibility may help point you to the right solutions.