Trace Minerals and Neurocognitive Optimization
Trace minerals affect neurotransmitter levels and neuroinflammation. Getting the right levels of micronutrients can help optimize neurocognitive function.
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ABCB1 (P-glycoprotein): Response to Medications, HRT, and Environmental Toxins
ABCB1 encodes P-glycoprotein, a transporter that removes toxins – and medications – from the body. Genetic variants in the ABCB1 gene can affect how well a medication works for you.
Tyramine Intolerance: Symptoms, High-Tyramine Foods, and Genetics
Tyramine intolerance happens when you can’t break it down. Too much tyramine can lead to a hypertensive crisis. Learn more and check your genetic raw data for results.
Plasminogen Activator Inhibitor-1 (PAI-1): Regulator of Clotting
Plasminogen Activator Inhibitor (PAI-1) is an important enzyme in the regulation of the breakdown of blood clots and fibrosis. Genetic variants impact the amount of PAI-1.
Hypnosis Genes: Genetic Influences on Hypnosis
Not everyone is equally susceptible to hypnosis. Learn how your genetic variants play a role in how your brain focuses and responds to hypnotic suggestions.
NLRP3: Genetic Variants that Increase Chronic Inflammation
Explore NLRP3 inflammasome genetics: How variants drive chronic inflammation in Alzheimer’s, diabetes, and autoimmune diseases. Discover triggers, health risks, and lifehacks like zinc & vitamin D to modulate it.
MTHFR Gene Explained: C677T and A1298C Variants, Testing, and Solutions
The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. It is a key gene in the methylation cycle.
Specialized Pro-resolving Mediators (SPMs): The Resolution of Inflammation
Chronic inflammation is at the root of all diseases. New research discusses how pro-resolving mediators are the key to the resolution of inflammation.
MAO-A & MAO-B: Monoamine Oxidase, Warrior Gene, and Mood
The MAOA and MAOB genes encode enzymes that break down certain neurotransmitters. People with low MAO may be prone to mood issues in certain circumstances.
Snoring: Genes and Solutions
Genetics plays a role in snoring —certain genes affect airway structure, fat distribution, and muscle control.
Alpha-Ketoglutarate (AKG) Supplements: What the Research Actually Shows [2026 Update]
Alpha-ketoglutarate for longevity: the science behind AKG supplements, including clinical trials, brain health, joint protection, supplement forms, and dosing.
Problems sleeping? Your genes can point to individualized solutions
Overview how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes.
Mast Cells: MCAS, Genetics, and Solutions
Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.
Carnitine: Genetic Variants Affecting Mitochondrial Energy and Health
Learn how carnitine powers cellular energy, supports organ health, and influences metabolism. Discover its benefits for brain, liver and immune function, plus how genetics affect your carnitine needs.
FTO and m6A Methylation
Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
Methylene Blue: Genetic Connections and Research Studies
Methylene blue has neuroprotective and anti-inflammatory properties, but it isn’t for everyone. Learn about the genetic variants that throw a caution flag on this one.
Glutamate Receptors and Transporters
Glutamate transporters and receptors carefully balance glutamate levels in the brain. Variants in the glutamate genes can affect how your brain balances glutamate.
Building Up Iron: Hemochromatosis Mutations
A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.
miRNA: What It Is and How It Works
miRNAs are small non-coding RNA molecules that regulate gene expression. They are important for healthy aging, longevity, metabolic health, and immune function.
Opioid Receptors Genetic Variants and Addiction
Genetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction. (Member’s article)
Resveratrol: Studies, Genetic Interactions, and Bioavailability
Resveratrol is a polyphenol with anti-inflammatory and antioxidant properties. Studies show that it affects heart health, bone health, cognitive function, and metabolic health.
Migraine Solutions Tailored to Your Genes: Triggers, Treatments, and Tools
Discover how genetics, triggers, and personalized strategies shape migraine prevention and relief. Find actionable solutions based on your DNA.
BPA and BPS: How Your Genes Influence Bisphenol Detoxification
BPA, a chemical found in some plastics, has been linked to a variety of health issues in people. Learn more about BPA and the research into genetic responses to this chemical.
Glutamate: Synthesis, transport, and supplement interactions
Glutamate is synthesized from glutamine or alpha-ketoglutarate. Imbalanced glutamate levels play a role in several neurological disorders.
Supplements with Genetic Connections
Linking supplements and genetic SNPs so that you can more easily find out what may work for you – and what to be cautious about.