Atrial fibrillation: Intersection of genetic susceptibility with inflammation and remodeling
Atrial fibrillation is an irregular heartbeat in the atrium. Genetic variants combine with inflammation and environmental triggers in causing A-fib.
Atrial fibrillation is an irregular heartbeat in the atrium. Genetic variants combine with inflammation and environmental triggers in causing A-fib.
Linking supplements and genetic SNPs so that you can more easily find out what may work for you – and what to be cautious about.
Glutathione is an antioxidant produced in all cells to balance out ROS. Genetic variants can impact your glutathione levels, which can alter your ability to detoxify certain substances or withstand stressors in the body.
Learn about the potential causes of fibromyalgia, including inflammation, genetics, and hypersensitivity to pain, along with overlapping conditions that complicate diagnosis.
Vitamin B6 is an important co-factor in hundreds of different enzymatic reactions. Low levels of B6 are linked to an increased risk of diabetes, cardiovascular disease, neurodegenerative diseases, and cancer. B6 is also essential for reducing oxidative stress and inflammation.
Neuropilins act as receptors and are found on the surface of cells. Learn about its many roles body, such as in the immune, vascular and nervous systems.
Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
BookmarkTired of guessing which vitamins and nutrients you need more of? Use your genetic raw data from 23andMe or AncestryDNA to find out! Here are five examples of how you can use your genetic data to understand how your genes can influence your need for specific nutrients. This is a … Read more
DAO enzyme supplements work by providing the enzyme needed to break down histamine in food and from the gut microbiome.
Discover the complex interplay of genetics and environment in ADHD susceptibility. Learn how circadian rhythm and neurotransmitter genes contribute to the disorder, and how toxicant exposure may increase risk.
You’re invited… …to steal my stuff! Genetic Lifehacks PRO members are free to reuse my article images (graphical overviews) on your social media sites. All I ask is that you give credit back to Genetic Lifehacks – a link, tag, note of where you … Read more
Genes and environmental factors combine to cause asthma. Learn how your genes impact the pathways involved in the different types of asthma.
Explore brain fog in detail, looking at the physiological causes, genetic susceptibility, and personalized solutions.
Tetrahydrobiopterin (BH4) is an essential cofactor in the production of neurotransmitters and nitric oxide. Genetic variants impact BH4 levels which can affect heart disease, cognitive function, and immune response.
Glyphosate is the active ingredient in the herbicide Round-Up. A recent study showed that people with CYP1A1 genetic variants are more likely to have problems with acetylcholinesterase inhibition from glyphosate.
Rosacea is a chronic inflammatory skin condition that is driven by upregulated inflammation. Learn how your genes interact with environmental factors to cause rosacea.
The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.
Biological pathways are complex to describe, and often a visual diagram makes it easier to conceptualize. This is an evolving Genetic Lifehacks project, so check back soon for more pathway diagrams and updates to current planners. Folate pathway (absorption, cellular cycles):
The MTHFD1 gene encodes an enzyme in the folate cycle. Genetic variants here can indicate a greater need for choline or folate in the diet.
Phthalates are a type of chemical used as plasticizers to make plastics more pliable. There has been a lot of research on the endocrine-disrupting effects of phthalates. Your genetic variants may impact whether phthalates are a problem for you.
Alpha-gal syndrome causes allergic reactions to meat (beef, pork, lamb) after being bitten by a tick. Find out why and which genetic pathways are involved.
Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.
Emulsifiers, found in many processed and packaged foods, can trigger an inflammatory response in the intestines based on whether you carry specific genetic variants.
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Long Covid is the persistence of symptoms after having COVID-19. Learn more about the underlying causes and treatments backed by the newest research.