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Vitamins & Nutrients: Exploring Nutrigenomics

Your genes influence how well your cells absorb, transport, and utilize nutrients. We are all genetically different, and your genes give you unique dietary needs and strengths. Genetic data can give you a starting point to know where you may need more – or less – of a specific nutrient. … Read more

Casein and Cow’s Milk Allergies

Casein and Cow’s Milk Allergies

Cow’s milk allergy can be due to your immune system responding to casein or β-lactoglobulin. Genetic variants in immune-system genes increase susceptibility – along with environmental factors.

Vitamin B6 deficiency genes, foods high in vitamin B6

Vitamin B6: Genetics, Absorption, and Deficiency

Vitamin B6 is an important co-factor in hundreds of different enzymatic reactions. Low levels of B6 are linked to an increased risk of diabetes, cardiovascular disease, neurodegenerative diseases, and cancer. B6 is also essential for reducing oxidative stress and inflammation.

HPA Axis disfunction, ways to reduce cortisol levels, genetic variants related to HPA Axis disfunction.

HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions

Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.

5 Genes that influence nutrition: MTHFR gene, FASD1 gene, LCT Gene BCO1 gene, Histamine Intolerance genes

5 Genes That Can Help You Dial In Your Diet

BookmarkTired of guessing which vitamins and nutrients you need more of? Use your genetic raw data from 23andMe or AncestryDNA to find out! Here are five examples of how you can use your genetic data to understand how your genes can influence your need for specific nutrients. This is a … Read more

Use My Images (PRO members)

You’re invited…              …to steal my stuff! Genetic Lifehacks PRO members are free to reuse my article images (graphical overviews) on your social media sites. All I ask is that you give credit back to Genetic Lifehacks – a link, tag, note of where you … Read more

Rosacea: Genetics, natural solutions, lifestyle and diet factors of rosacea

Rosacea, Genetics, and Solutions

Rosacea is a chronic inflammatory skin condition that is driven by upregulated inflammation. Learn how your genes interact with environmental factors to cause rosacea.

MTHFR mutations explained, frequency of C677T SNP, A1298C SNP, Supplement Interaction, MTHFR variant risks

MTHFR Mutation: What is it? How to check your raw data.

The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.

Pathway Diagrams

Biological pathways are complex to describe, and often a visual diagram makes it easier to conceptualize. This is an evolving Genetic Lifehacks project, so check back soon for more pathway diagrams and updates to current planners.  Folate pathway (absorption, cellular cycles):

MTHFD1: Folate cycle and Choline

MTHFD1: Folate and Choline

The MTHFD1 gene encodes an enzyme in the folate cycle. Genetic variants here can indicate a greater need for choline or folate in the diet.

Phthalate detoxification pathway, phthalate genetic interaction, phthalate overview

Phthalates: Genes, Diet, and Detoxification Pathways

Phthalates are a type of chemical used as plasticizers to make plastics more pliable. There has been a lot of research on the endocrine-disrupting effects of phthalates. Your genetic variants may impact whether phthalates are a problem for you.

Estrogen metabolism, estrogen metabolites that increase cancer risk, estrogen genetic variants, steps to keep estrogen in balance

Estrogen: How It Is Made and How We Get Rid of It

Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.