Candida Biology, Pathogenesis, and Genetic Susceptibility
Learn why genetic variants in IL‑17, TLRs, dectin‑1, MBL, FUT2, and STAT1 can make some people much more susceptible to chronic or severe Candida infections.
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ME/CFS and Genetics: Chronic Fatigue Syndrome Genes, Immune Pathways, and Natural Solutions
Genetic variants in immune, mitochondrial, and inflammatory pathways (NK cells, NLRP3, interferon, complement, TRP channels) increase ME/CFS susceptibility. Check your genes and explore research-backed solutions.
T Cell Exhaustion in Long COVID, ME/CFS, and Cancer: Mechanisms and Solutions
T cell exhaustion reduces your immune response in chronic infections, long Covid, and cancer. Check your genes, read the new studies on interventions, and understand the mechanisms.
Urolithin A for Mitochondrial Health and Muscle Function: Genetic Connections and Research Studies
Urolithin A supports mitochondrial function and muscle health. Discover how your gut produces it, who benefits most from supplements, and what the research shows.
PFAS, Your Genes, and Your Health: From Mitochondrial Function to Immune Response
PFAS “forever chemicals” accumulate in blood and tissue and resist normal clearance. This article covers their health effects and the genetic factors that shape individual susceptibility.
Dry Eyes: Using Genetic Data to Find the Right Solutions
Use your genetic data to understand the root causes of dry eyes, from immune response to meibomian glands, and explore research-backed options to relieve symptoms.
Vitamin B6: Genetics, Absorption, and Deficiency
Vitamin B6 is an important co-factor in hundreds of different enzymatic reactions. Low levels of B6 are linked to an increased risk of diabetes, cardiovascular disease, neurodegenerative diseases, and cancer. B6 is also essential for reducing oxidative stress and inflammation.
Neuropilins: Neurodevelopmental Disorders, Gut Barrier, & Covid Brain
Explore how neuropilin variants shape neurodevelopment, vascular permeability, gut barrier function, viral entry (SARS‑CoV‑2, EBV, CMV), and risks for autoimmunity and cancer.
BPC-157: Tendon Repair and More
BPC-157 (body protection compound-157) is a peptide derived from human gastric juice that is 15 amino acids in length. Studies show that it promotes the healing of different tissues, including skin, muscle, bone, and tendons.
ABCB1 (P-glycoprotein): Response to Medications, HRT, and Environmental Toxins
ABCB1 encodes P-glycoprotein, a transporter that removes toxins – and medications – from the body. Genetic variants in the ABCB1 gene can affect how well a medication works for you.
Tyramine Intolerance: Symptoms, High-Tyramine Foods, and Genetics
Tyramine intolerance happens when you can’t break it down. Too much tyramine can lead to a hypertensive crisis. Learn more and check your genetic raw data for results.
POTS: Genetics, Causes, and Solutions for Postural Orthostatic Tachycardia Syndrome
Explore the genetic basis of POTS, from HLA and norepinephrine transporter variants to EDS, MCAS, and long Covid connections, plus strategies to better manage symptoms.
VMAT2 gene: The God Gene and Neurotransmitters
VMAT2, the so‑called “God gene,” packages dopamine, serotonin, and other monoamines into vesicles, protecting neurons from oxidative stress and influencing risks for Parkinson’s, PTSD, alcohol dependence, and diabetes.
PAI-1 (SERPINE1): Genetic Variants, Blood Clot Risk, Fibrosis, and Natural PAI-1 Inhibitors
Plasminogen Activator Inhibitor (PAI-1) is an important enzyme in the regulation of the breakdown of blood clots and fibrosis. Genetic variants impact the amount of PAI-1.
Polycythemia Vera: Understanding Inherited and Somatic Mutations behind This Rare Blood Disorder
Polycythemia vera: See how your genetics and environment contribute to this rare blood disorder. Understand the causes, risks, and role of inheritance.
Oxalates: What Your Genes and Diet Say About Oxalate Health Issues
Green smoothies have been a health fad for quite a while now, but these health drinks can be a double-edged sword for some people due to their high oxalate content. Find out if you are genetically prone to kidney stones and what to do about it.
Ehlers Danlos Syndrome: Genes, Types, and Treatments
Ehlers-Danlos Syndromes causes changes in the way that collagen forms in the joints, ligaments, and skin. Explore the research on EDS and the genetic mutations that cause some of the subtypes of the disorder.
Cordyceps: Clinical Trials, Mechanism of Action, and Genetic Connections
Cordyceps mushroom extract has immunomodulatory and anti-inflammatory effects. Studies show benefits for asthma, resistance training, endurance training, and kidney disease.
MTHFR Gene Explained: C677T and A1298C Variants, Testing, and Solutions
The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. It is a key gene in the methylation cycle.
Specialized Pro-resolving Mediators (SPMs): The Resolution of Inflammation
Chronic inflammation is at the root of all diseases. New research discusses how pro-resolving mediators are the key to the resolution of inflammation.
Snoring: Genes and Solutions
Genetics plays a role in snoring —certain genes affect airway structure, fat distribution, and muscle control.
Mast Cells: MCAS, Genetics, and Solutions
Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.
Alpha-Gal Syndrome: Meat Allergy, Tick Bites, and Genetics
Alpha-gal syndrome causes allergic reactions to meat (beef, pork, lamb) after being bitten by a tick. Find out why and which genetic pathways are involved.
Pregnancy: How Your Genes affect the Nutrients You Need
Pregnancy is a time of increased nutritional needs, and your genes can help you dial in your diet to prevent nutrient deficiencies.
FTO and m6A Methylation
Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.