Candida Biology, Pathogenesis, and Genetic Susceptibility
Learn why genetic variants in IL‑17, TLRs, dectin‑1, MBL, FUT2, and STAT1 can make some people much more susceptible to chronic or severe Candida infections.
Learn why genetic variants in IL‑17, TLRs, dectin‑1, MBL, FUT2, and STAT1 can make some people much more susceptible to chronic or severe Candida infections.
Genetic variants in immune, mitochondrial, and inflammatory pathways (NK cells, NLRP3, interferon, complement, TRP channels) increase ME/CFS susceptibility. Check your genes and explore research-backed solutions.
T cell exhaustion reduces your immune response in chronic infections, long Covid, and cancer. Check your genes, read the new studies on interventions, and understand the mechanisms.
Urolithin A supports mitochondrial function and muscle health. Discover how your gut produces it, who benefits most from supplements, and what the research shows.
PFAS “forever chemicals” accumulate in blood and tissue and resist normal clearance. This article covers their health effects and the genetic factors that shape individual susceptibility.
Use your genetic data to understand the root causes of dry eyes, from immune response to meibomian glands, and explore research-backed options to relieve symptoms.
Explore how neuropilin variants shape neurodevelopment, vascular permeability, gut barrier function, viral entry (SARS‑CoV‑2, EBV, CMV), and risks for autoimmunity and cancer.
BPC-157 (body protection compound-157) is a peptide derived from human gastric juice that is 15 amino acids in length. Studies show that it promotes the healing of different tissues, including skin, muscle, bone, and tendons.
ABCB1 encodes P-glycoprotein, a transporter that removes toxins – and medications – from the body. Genetic variants in the ABCB1 gene can affect how well a medication works for you.
Tyramine intolerance happens when you can’t break it down. Too much tyramine can lead to a hypertensive crisis. Learn more and check your genetic raw data for results.
VMAT2, the so‑called “God gene,” packages dopamine, serotonin, and other monoamines into vesicles, protecting neurons from oxidative stress and influencing risks for Parkinson’s, PTSD, alcohol dependence, and diabetes.
Plasminogen Activator Inhibitor (PAI-1) is an important enzyme in the regulation of the breakdown of blood clots and fibrosis. Genetic variants impact the amount of PAI-1.
Polycythemia vera: See how your genetics and environment contribute to this rare blood disorder. Understand the causes, risks, and role of inheritance.
Green smoothies have been a health fad for quite a while now, but these health drinks can be a double-edged sword for some people due to their high oxalate content. Find out if you are genetically prone to kidney stones and what to do about it.
Cordyceps mushroom extract has immunomodulatory and anti-inflammatory effects. Studies show benefits for asthma, resistance training, endurance training, and kidney disease.
The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. It is a key gene in the methylation cycle.
Chronic inflammation is at the root of all diseases. New research discusses how pro-resolving mediators are the key to the resolution of inflammation.
Genetics plays a role in snoring —certain genes affect airway structure, fat distribution, and muscle control.
Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.
Alpha-gal syndrome causes allergic reactions to meat (beef, pork, lamb) after being bitten by a tick. Find out why and which genetic pathways are involved.
Pregnancy is a time of increased nutritional needs, and your genes can help you dial in your diet to prevent nutrient deficiencies.
Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
Smarter, happier, and more focused — this section pulls together the articles on how your genetic variants impact brain function and mental health. Instead of generic advice, you’ll find research‑based explanations of how specific SNPs influence neurotransmitters, mood, cognition, and addiction risk — plus practical, low‑hype options you can try. … Read more
Two natural fibrinolytics to reduce clotting are nattokinase and lumbrokinase. Learn more about these options based upon the newest research and clinical trials.
Your genes influence how well your cells absorb, transport, and utilize nutrients. We are all genetically different, and your genes give you unique dietary needs and strengths. Genetic data can give you a starting point to know where you may need more – or less – of a specific nutrient. … Read more