Study: MWF of the corpus callosum is a robust measure of remyelination: Results from the ReBUILD trial Published: PNAS, May 2023 Overview: The study included 50 multiple sclerosis (MS patients) and looked at the brain regions that are rich in myelin. In MS, the body attacks the myelin sheath. The study looked at ways to assess the therapeutic effect of compounds on the remyelination of neurons through imaging. While important for researchers to know the best MRI imaging biomarkers, what I found interesting is the effect on myelin from a first-generation anti-histamine, clemastine. MRI scans were done at baseline, 3 months and 5 months. Half of the patients received clematine and the other half a placebo from months 3 to 5. The results showed that clemastine stimulated the differentiation of stem cells that make myelin. This isn’t the first study on clemastine showing positive results for people with MS. However, it is important in that it shows how and where the remyelination is taking place. Clemastine used to be available OTC in the US as Dayhist Allergy and … Read more
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It can be difficult sometimes to come up with new breakfast ideas for a low histamine diet. Here is a recipe for a low histamine smoothie bowl for a quick breakfast. (Member’s article)
On a low histamine diet and craving salsa and tortilla chips? Here is a quick recipe for a low histamine salsa using roasted red peppers instead of tomatoes.
Looking for low histamine treats? Here is a mint shake recipe low in histamines, and an excellent source of luteolin, a mast cell stabilizer.
Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.