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 Plant Compounds for SARS-CoV-2

Research Studies on Plant Compounds for SARS-CoV-2

This article explains the current research (August 2021) on natural compounds that may help to combat SARS-CoV-2. Included are clinical trial results on nigella sativa, curcumin, and quercetin.

Genetic Lifehacks Annual Membership

Annual membership is $79.99 a year — about $6.67 a month. Here’s what a year of  membership gives you: Access every article in full, including the genotype sections and the Lifehacks at the end, where the research turns into things you can actually try. See your own results in each … Read more

IgE-mediated Food Allergies, non-IgE-mediated Food Allergies

Genetics and Food Allergies

Do you have a food allergy? Discover how environmental factors and genetic susceptibility can shape individual reactions.

COVID-19 & Genetics

COVID-19 & Genetics: Who gets sick and why?

Not everyone gets sick when exposed to the SARS-CoV-2 virus. While there are many factors that come into play here, research points to genetics as playing a role. Several good genetic studies have recently been released showing which genes are important in COVID-19 susceptibility. Learn more and check your genes.

CBD Oil: Will it Work for You?

CBD Oil: Will it work for you?

Why do some people get such great benefits from CBD while others notice nothing? Your genes play a role in how your body responds to CBD.

Sleep Report: Genetic Causes of Sleep Problems

This is a quick (Member’s Only) overview of how your genetic variants impact various aspects of sleep including insomnia, circadian rhythm, and sleep quality.

What is Genetic Lifehacks?

My goal is to help you understand how to make the necessary changes to solve a health challenge or customize your diet for optimal health-all based on your genes. You can use raw genetic data from 23andMe, AncestryDNA, MyHeritage, etc. Genetic Lifehacks focuses on three key strategies: Learn, Experiment, and … Read more

MTHFR c677t, symptoms and solutions

MTHFR: How to check your data for C677T and A1298C

Key takeaways: The MTHFR enzyme converts folate (vitamin B9) to its active form, 5-MTHF. Folate is used to create methyl groups, which cells use to synthesize neurotransmitters, detoxify toxicants, methylate DNA, and maintain a healthy heart. The common MTHFR C677T and A1298C variants lower enzyme function (up to ~70–80% for … Read more

How HMGB1 acts as an alarmin, escalating the inflammatory response to infection and injury

HMGB1 gene: Inflammatory Response Protein and COVID-19

The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.

NOS3: Heart Health, Blood Pressure, and Healthy Aging

Nitric Oxide Synthase (NOS3): Heart Health, Blood Pressure, and Healthy Aging

Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.

Lupus: Genetics, Root Causes, and Possible Solutions

Lupus: Genetics, Root Causes, and Possible Solutions

Lupus is a complex autoimmune disease that can impact several different systems in your body. Learn more about how your genetic variants impact the “why” for this autoimmune disease.

Allergy Medicine: Why Fexofenadine Works Better for Some People

Allergy Medicine: Why Fexofenadine Works Better for Some People

Ever wonder why a certain medication may work great for a friend and do nothing for you? One reason could be the genes involved in transporting the medication into and out of your cells. This article looks at the research studies on fexofenadine and the Multidrug Resistance Protein variants.

Fisetin: Antioxidant and Senolytic

Fisetin: Antioxidant and Senolytic

Fisetin is a natural flavonol found in several types of fruits and vegetables and may prove to be a critical anti-aging component. In several recent studies, fisetin clears out senescent cells holding a lot of promise for healthy aging. Learn more about the newest research into this possible longevity compound.

Genetic Lifehacks Membership

Genetic Lifehacks Membership Your DNA has answers. Here’s how to read them. See your own genotype inside 420+ research-based articles, print summary reports on the topics you care about, and figure out which diet, supplement, and lifestyle changes actually fit your genes. See membership options Your data never leaves your … Read more

Genetics and Alcohol Metabolism

Alcohol Metabolism: ALDH2 and ADH1B Genes

Wondering why you don’t react the same way to alcohol as your friends do? Some people metabolize alcohol faster leaving a build-up of acetaldehyde. Learn more about why this can be a health problem for some.

Publications

Research Publications by Debbie Moon, MSc, researcher, Genetic Lifehacks A Mixed-Methods Single-Case Study of Chronic Multisystem Symptoms and a DNA2 Variant: Integrating Narrative and Empirical Data to Explore Possible Mitochondrial Bioenergetic Vulnerability (second author) Books by Debbie Moon: Histamine Lifehacks: Histamine in Balance: From Biological Roles to Managing Histamine Intolerance  … Read more

Genes and Early Morning Insomnia

Do you Wake up at 4 AM? Genetic Variants of Morning Insomnia

Seeing 3:30 or 4:00 on your clock each morning? There could be a physiological reason for this. Learn about the genetic variants linked to early waking insomnia and the connection to depression. (Member’s article)