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What is Genetic Lifehacks?

My goal is to help you understand how to make the necessary changes to solve a health challenge or customize your diet for optimal health-all based on your genes. You can use raw genetic data from 23andMe, AncestryDNA, MyHeritage, etc. Genetic Lifehacks focuses on three key strategies: Learn, Experiment, and … Read more

MTHFR c677t, symptoms and solutions

MTHFR: How to check your data for C677T and A1298C

Key takeaways: The MTHFR enzyme converts folate (vitamin B9) to its active form, 5-MTHF. Folate is used to create methyl groups, which cells use to synthesize neurotransmitters, detoxify toxicants, methylate DNA, and maintain a healthy heart. The common MTHFR C677T and A1298C variants lower enzyme function (up to ~70–80% for … Read more

HMGB1: From Nuclear Organizer to Inflammatory Alarmin

HMGB1 gene: inflammatory response protein important in sepsis and COVID-19

The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.

NOS3: Heart Health, Blood Pressure, and Healthy Aging

Nitric Oxide Synthase (NOS3): Heart Health, Blood Pressure, and Healthy Aging

Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.

Lupus: Genetics, Root Causes, and Possible Solutions

Lupus: Genetics, Root Causes, and Possible Solutions

Lupus is a complex autoimmune disease that can impact several different systems in your body. Learn more about how your genetic variants impact the “why” for this autoimmune disease.

Allergy Medicine: Why Fexofenadine Works Better for Some People

Allergy Medicine: Why Fexofenadine Works Better for Some People

Ever wonder why a certain medication may work great for a friend and do nothing for you? One reason could be the genes involved in transporting the medication into and out of your cells. This article looks at the research studies on fexofenadine and the Multidrug Resistance Protein variants.

Fisetin: Antioxidant and Senolytic

Fisetin: Antioxidant and Senolytic

Fisetin is a natural flavonol found in several types of fruits and vegetables and may prove to be a critical anti-aging component. In several recent studies, fisetin clears out senescent cells holding a lot of promise for healthy aging. Learn more about the newest research into this possible longevity compound.

Genetics and Alcohol Metabolism

Alcohol Metabolism: ALDH2 and ADH1B Genes

Wondering why you don’t react the same way to alcohol as your friends do? Some people metabolize alcohol faster leaving a build-up of acetaldehyde. Learn more about why this can be a health problem for some.

Publications

Estrogen: How it is Made and How We Get Rid of It NQO1 Gene: Metabolism of quinones, benzene, and more Dopamine Receptor Genes How natural supplements can change circadian gene expression Restless Leg and Periodic Limb Movement Disorder: Genetic Solutions NAD+ Reversing Aging? Overview of NR and NMN Histamine Intolerance … Read more

Genes and Early Morning Insomnia

Do you Wake up at 4 AM? Genetic Variants of Morning Insomnia

Seeing 3:30 or 4:00 on your clock each morning? There could be a physiological reason for this. Learn about the genetic variants linked to early waking insomnia and the connection to depression. (Member’s article)

Genetics of Grass and Pollen Allergies

Are you allergic to grass pollen? It may be genetic.

Allergies are usually due to a mix of genetic susceptibility and being exposed to certain triggering molecules. Several different gene variants have ties to an increased risk of grass pollen allergies.

Articles Directory – Genetic Lifehacks

Every published article on geneticlifehacks.com, grouped by topic. 502 articles  ·  50 topics Expand all Collapse all Addiction4 Alzheimer's Prevention16 Arrhythmia & Heart Function10 Athletics & Exercise12 Autoimmune Diseases23 Blood Pressure6 Brain and Mood55 Cancer Prevention12 Carbohydrate Metabolism4 Cholesterol & Lipids10 Chronic Inflammation12 Clotting & Blood13 Cognitive Function15 COVID, Long … Read more

Videos: Quick Overviews of Using Your Genetic Data

Check out the Genetic Lifehack’s YouTube channel and subscribe for updates. A quick tutorial on how to locate your genotypes when reading our articles. By following a few easy steps, you will quickly discover how to relate the articles and topics for your specific genes. Tutorial on how to download … Read more