Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
Smarter, happier, and more focused — this section pulls together the articles on how your genetic variants impact brain function and mental health. Instead of generic advice, you’ll find research‑based explanations of how specific SNPs influence neurotransmitters, mood, cognition, and addiction risk — plus practical, low‑hype options you can try. … Read more
Two natural fibrinolytics to reduce clotting are nattokinase and lumbrokinase. Learn more about these options based upon the newest research and clinical trials.
Your genes influence how well your cells absorb, transport, and utilize nutrients. We are all genetically different, and your genes give you unique dietary needs and strengths. Genetic data can give you a starting point to know where you may need more – or less – of a specific nutrient. … Read more
Cow’s milk allergy can be due to your immune system responding to casein or β-lactoglobulin. Genetic variants in immune-system genes increase susceptibility – along with environmental factors.
Discover how genetics, triggers, and personalized strategies shape migraine prevention and relief. Find actionable solutions based on your DNA.
Explore how MEFV mutations drive autoinflammatory flares, the overlap of FMF with fibromyalgia, gout, lupus, and MCAS, and evidence-based options from colchicine to natural anti-inflammatory strategies.
Atrial fibrillation is an irregular heartbeat in the atrium. Genetic variants combine with inflammation and environmental triggers in causing A-fib.
Mushrooms contain a healthy antioxidant called ergothioneine. But for people with a SLC22A4 genetic variant, this antioxidant can be too much of a good thing, leading to intestinal problems. Check your genetic data to see if you carry this mushroom intolerance variant.
Linking supplements and genetic SNPs so that you can more easily find out what may work for you – and what to be cautious about.
Glutathione is an antioxidant produced in all cells to balance out ROS. Genetic variants can impact your glutathione levels, which can alter your ability to detoxify certain substances or withstand stressors in the body.
Learn about the potential causes of fibromyalgia, including inflammation, genetics, and hypersensitivity to pain, along with overlapping conditions that complicate diagnosis.
Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
BookmarkTired of guessing which vitamins and nutrients you need more of? Use your genetic raw data from 23andMe or AncestryDNA to find out! Here are five examples of how you can use your genetic data to understand how your genes can influence your need for specific nutrients. This is a … Read more
DAO enzyme supplements work by providing the enzyme needed to break down histamine in food and from the gut microbiome.
Discover the complex interplay of genetics and environment in ADHD susceptibility. Learn how circadian rhythm and neurotransmitter genes contribute to the disorder, and how toxicant exposure may increase risk.
You’re invited… …to steal my stuff! Genetic Lifehacks PRO members are free to reuse my article images (graphical overviews) on your social media sites. All I ask is that you give credit back to Genetic Lifehacks – a link, tag, note of where you … Read more
Genes and environmental factors combine to cause asthma. Learn how your genes impact the pathways involved in the different types of asthma.
Brain fog has many roots: nutrient deficiencies, hypoxia, inflammation, viral infections, microclots, histamine, amino acid metabolism, and genetics — plus targeted strategies to restore clear thinking.
Tetrahydrobiopterin (BH4) is an essential cofactor in the production of neurotransmitters and nitric oxide. Genetic variants impact BH4 levels which can affect heart disease, cognitive function, and immune response.
Glyphosate is the active ingredient in the herbicide Round-Up. A recent study showed that people with CYP1A1 genetic variants are more likely to have problems with acetylcholinesterase inhibition from glyphosate.
Rosacea is a chronic inflammatory skin condition that is driven by upregulated inflammation. Learn how your genes interact with environmental factors to cause rosacea.
Biological pathways are complex to describe, and often a visual diagram makes it easier to conceptualize. This is an evolving Genetic Lifehacks project, so check back soon for more pathway diagrams and updates to current planners. Folate pathway (absorption, cellular cycles):
The MTHFD1 gene encodes an enzyme in the folate cycle. Genetic variants here can indicate a greater need for choline or folate in the diet.
Phthalates are a type of chemical used as plasticizers to make plastics more pliable. There has been a lot of research on the endocrine-disrupting effects of phthalates. Your genetic variants may impact whether phthalates are a problem for you.