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Estrogen metabolism, estrogen metabolites that increase cancer risk, estrogen genetic variants, steps to keep estrogen in balance

Estrogen: How It Is Made and How We Get Rid of It

Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.

CYP2B6 drug and supplement interaction - part of CYP450 family of genes

CYP2B6: Genetic Variants That Interact with Medications

The CYP2B6 enzyme is part of the body’s first line of defense in detoxifying and breaking down certain and important for metabolizing several medications. Genetic variants of this enzyme can either speed up or slow down its function.

CYP2C8: Phase 1 Detoxification and Medication Interaction

CYP2C8: Prescription Medications and Arachidonic Acid

The CYP2C8 gene is important in the metabolism of several chemotherapy drugs as well as playing a role in the metabolism of NSAIDs. Genetic variants that alter how this enzyme works can impact your reaction to a medication.

Tyramine Intolerance: Metabolism of Tyramine, MAOA, FMO3, and CYP2D6 enzymes, foods high in tyramine

Tyramine Intolerance: Metabolism of Tyramine

Tyramine intolerance happens when you can’t break it down. Too much tyramine can lead to a hypertensive crisis. Learn more and check your genetic raw data for results.

CYP3A4 Gene: CYP450 Family of Genes, Medication Metabolism and Vitamin D Interaction

CYP3A4 Gene: Impacting Prescription Drugs

The CYP3A family of genes is involved in metabolizing about half of the drugs on the market today. Check your genes to see if you carry variants that impact the speed at which you metabolize medications.

CYP2C9 Medication Metabolism Gene, CYP2C9 Variants, CYP450 Family of genes

CYP2C9: Genetic Variants and Drug Metabolism

Have you ever wondered why certain medications don’t work well for you? Genetic variants can change how fast or how slow the medication is broken down in your body. Learn how the CYP2C9 variants impact quite a few prescription medications.

CYP2A6 Nicotine and Medication Metabolism

CYP2A6: Breaking down nicotine and other medications

How many cigarettes a day a person smokes – and how hard it is for them to quit – is at least partly dependent on the CYP2A6 gene. This enzyme also metabolizes several important cancer drugs.

Should you eat organic? Detoxifying Neonicotinoids

Is buying organic worth the extra cost? Pesticides that are sprayed on conventionally grown foods affect people differently. Some people carry genetic variants that decrease their ability to detoxify specific pesticides, others may be more resilient. This is Part One in a multipart series on pesticide detoxification. (Member’s article)