Genotype Summary Report: Vitamins

[mepr-show rules=”23265″  unauth=”message”]


No Entries Found

You do not have permission to view this form.

Article Gene RS ID Risk Allele Your Genotype Notes About Risk Allele
MTHFR MTHFR C677T rs1801133 A 40-70% decrease in MTHFR enzyme function (folate metabolism)
MTHFR MTHFR A1298C rs1801131 G 10-20% decrease in MTHFR enzyme function (folate metabolism)
Vitamin B12 MTRR rs1801394 G Decreased MTRR, affects B12
Vitamin B12 FUT2 rs601338 A AA only: non-secretor, serum B12 tests may be inaccurate
Vitamin B12 TCN1 rs526934 G B12 transporter, lower circulating B12
Vitamin B12 TCN2 rs9606756 G B12 binding protein, reduced B12 levels
Riboflavin MTHFR rs1801133 A Riboflavin may help lower homocysteine
Riboflavin FMO3 rs1736557 A Decreased FMO3; riboflavin may help
Riboflavin FMO3 rs28363581 C Decreased FMO3; riboflavin may help
Riboflavin FMO3 rs3832024 D Decreased FMO3; riboflavin may help
Riboflavin FMO3 rs2266782 A Decreased FMO3; riboflavin may help
Riboflavin FMO3 rs909530 T Decreased FMO3; riboflavin may help
Riboflavin FMO3 rs2266780 G Decreased FMO3; riboflavin may help
Riboflavin FMO3 rs61753344 T Decreased FMO3; riboflavin may help
Riboflavin FMO3 rs909530 T Decreased FMO3; riboflavin may help
Riboflavin ETFDH i5007876 A Multiple ACAD (rare)
Riboflavin SLC52A3 i5008314 A Brown-Vialetto-Van Laere (rare)
Riboflavin SLC25A32 rs147014855 T Exercise intolerance that responds to riboflavin
Vitamin B6 ALPL rs1256335 G Decreased vitamin B6
Vitamin B6 ALPL rs1697421 T Slightly decreased vitamin B6 levels
Vitamin B6 ALPL rs1780316 T Slightly decreased vitamin B6 levels
Vitamin B6 ALPL rs4654748 C Slightly decreased vitamin B6 levels
Vitamin B6 ALDH7A1 rs121912707 G Mutation linked to vitamin B6 dependent epilepsy (rare)
Vitamin B6 ALDH7A1 rs121912708 A rare mutation linked to vitamin B6 dependent epilepsy
Vitamin C SLC23A1 rs6133175 G Higher plasma vitamin C levels
Vitamin C SLC23A1 rs12479919 T Higher plasma vitamin C levels
Vitamin C SLC23A1 rs6053005 T Higher plasma vitamin C levels
Vitamin C SLC23A1 rs33972313 T Lower plasma vit. C
Vitamin C SLC23A1 rs10063949 C Lower plasma vit. C
Vitamin C SLC23A1 rs33972313 T Lower plasma vit. C
Biotin (B7) BTD rs13078881 C Reduced enzyme activity
Biotin (B7) BTD rs28934601 G Mutation related to biotin deficiency (rare)
Biotin (B7) BTD rs13073139 A Mutation related to biotin deficiency (rare)
Biotin (B7) BTD rs80338684 T Mutation related to biotin deficiency (rare)
Biotin (B7) BTD rs34885143 A Mutation related to biotin deficiency (rare)
Zinc IL-6 rs1800795 G Zinc modulates inflammation
Zinc SLC30A8 rs13266634 T Zinc may decrease blood glucose (if high)
Zinc SLC30A8 rs11558471 A Zinc may decrease blood glucose (if high)
Zinc SLC30A2 rs587776926 C Zinc transporter deficiency
Zinc SLC30A2 rs185398527 T Zinc transporter deficiency
Zinc SLC30A2 rs117153535 A Zinc transporter deficiency
Zinc SLC39A2 rs2234632 T Zinc reduces inflammation
Zinc SLC39A13 rs121434363 A Mutation linked to Ehlers-Danlos, zinc dependent
Zinc CA1 rs1532423 A AA: higher serum zinc
Thiamine (B1) SLC19A2 rs2038024 C Increased risk of venous thromboembolism
Thiamine (B1) SLC19A2 rs28937595 A Mutation linked to thiamine-responsive megoblastic anemia (rare)
Thiamine (B1) SLC19A2 rs121908540 A Mutation linked to thiamine-responsive megoblastic anemia (rare)
Thiamine (B1) SLC19A2 rs74315373 A Mutation linked to thiamine-responsive megoblastic anemia (rare)
Thiamine (B1) SLC19A2 rs74315374 T Mutation linked to thiamine-responsive megoblastic anemia (rare)
Thiamine (B1) SLC19A2 rs74315375 T Mutation linked to thiamine-responsive megoblastic anemia (rare)
Thiamine (B1) SLC19A3 rs121917884 C Mutation related to basal ganglia disease (rare)
Thiamine (B1) SLC19A3 rs121917882 A Mutation related to basal ganglia disease (rare)
Thiamine (B1) SLC22A1 rs72552763 D reduced thiamine transport
Thiamine (B1) TPK1 rs371271054 C Carrier of thiamine-related mutation
Thiamine (B1) SLC25A19 rs119473030 G Mutation for microcephaly
Thiamine (B1) PHDC rs28933391 A AA = pathogenic for Pyruvate dehydrogenase deficiency (Important)
Thiamine (B1) PHDC rs28935769 C CC = pathogenic for Pyruvate dehydrogenase deficiency (important)
Thiamine (B1) BCKDHB i3002808 C Maple syrup urine disease, thiamine responsive (rare)
Thiamine (B1) BCKDHB rs386834233 A Maple syrup urine disease, thiamine responsive (rare)
Thiamine (B1) BCKDHB rs74103423 A Maple syrup urine disease, thiamine responsive (rare)
Choline PEMT rs7946 T Decreased PEMT activity, phosphatidylcholine
Choline CHKA rs10791957 A Reduced turnover of methionine to phosphatidylcholine
Choline BHMT rs3733890 A Decreased conversion of choline to betaine
Choline FMO3 rs2266782 A Choline used less as a methyl donor
Choline MTHFD1 rs2236225 A More likely to have choline deficiency (check diet)
Vitamin A BCMO1 rs7501331 T Decreased beta-carotene conversion to active form of vitamin A
Vitamin A BCMO1 rs12934922 T Decreased beta-carotene conversion to active form of vitamin A
Vitamin A BCMO1 rs11645428 G Decreased beta-carotene conversion to active form of vitamin A
Vitamin A BCMO1 rs6420424 A Decreased beta-carotene conversion to active form of vitamin A
Vitamin A BCMO1 rs6564851 G Decreased beta-carotene conversion to active form of vitamin A
Vitamin D CYP2R1 rs2060793 A Lower vitamin D levels
Vitamin D CYP2R1 rs1562902 T Higher vitamin D levels
Vitamin D CYP27B1 rs28934607 A Pathogenic for vitamin D related rickets (important)
Vitamin D CYP27B1 rs28934605 T Pathogenic for vitamin D related rickets (important)
Vitamin D CYP27B1 rs28934604 T Pathogenic for vitamin D related rickets (important)
Vitamin D GC rs2282679 G Lower vitamin D levels
Vitamin D GC rs7041 A Lower vitamin D levels
Vitamin D VDR rs731236 A Lower vitamin D levels, VDR-Taql
Vitamin D VDR rs1544410 T Lower vitamin D levels, VDR-Bsml
Vitamin D VDR rs2228570 G Lower vitamin D levels, VDR Fokl
Vitamin D VDR rs7975232 C VDR Apal variant
Folic Acid Conversion DHFR rs70991108 D More unmetabolized folic acid in blood
Folic Acid Conversion DHFR rs1677693 T Affects folic acid metabolism; folic acid supplementation may increase colon cancer risk
Folic Acid Conversion DHFR rs1650697 A Decreased conversion of folic acid, alters methotrexate response
Folic Acid Conversion MTHFR rs1801133 A Reduced MTHFR efficiency, may need more folate, B12
Vitamin K CYP4F2 rs2108622 T Reduced CYP4F2, possibly __ warfarin dosage
Vitamin K CYP4F2 rs1558139 A Lower risk of stroke (inc. vit. K)
Vitamin K VKORC1 rs9934438 G Decreased VKORC1
Selenium SEP15 rs5845 A Decreased selenium transport; increased risk of lung cancer in people with lower selenium levels, lower verbal memory scores
Selenium SEP15 rs561104 C Decreased FMO3, which breaks down nitrogen-containing amines.  Some people helped with riboflavin.
Selenium SEPP1 rs7579 T Lower serum selenium levels, increased risk of prostate cancer
Selenium SEPP1 rs3877899 T Lower serum selenium levels
Selenium SELENOS rs34713741 T Increased risk of colon and gastric cancers
Selenium GPX4 rs713041 T Altered GPX4 function, increased risk of colon cancer or breast cancer with low selenium
Selenium GPX1 rs1050450 A Lower GPX enzyme activity
MTHFR Beyond C677T and A1298C MTHFR rs2274976 T Decreased folate conversion; increased risk of cleft lip, schizophrenia, high homocysteine
MTHFR Beyond C677T and A1298C MTHFR rs9651118 C Decreased risk of liver cancer, lower homocysteine (good)
MTHFR Beyond C677T and A1298C MTHFR rs13306560 T Lower blood pressure, protective against Parkinson’s (good)
MTHFR Beyond C677T and A1298C MTHFR rs17367504 G Protective against hypertension and preeclampsia (good)
MTHFR Beyond C677T and A1298C MTHFR rs4846049 G GG: Decreased risk of migraines (good)

Disclaimer: The information provided in the report and by Genetic Lifehacks is for informational purposes only. It is not intended to diagnose or treat any disease. Please visit GeneticLifehacks.com for more detailed information plus complete references.
[/mepr-show]