Homocysteine: Genetics, High Homocysteine Levels, and Solutions
High homocysteine levels are strongly linked to an increased relative risk of cardiovascular diseases. Find out how your genes impact homocysteine levels.
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Dopamine Synthesis SNPs: Genes, lifestyle, diet, and dopamine optimization
Two key enzymes are needed for dopamine synthesis. Genetics, diet, and lifestyle can influence your dopamine production.
Creatine: Boosting Muscles and Increasing Brain Power
Creatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.
Phthalates: Genes, Diet, and Detoxification Pathways
Phthalates are a type of chemical used as plasticizers to make plastics more pliable. There has been a lot of research on the endocrine-disrupting effects of phthalates. Your genetic variants may impact whether phthalates are a problem for you.
Biotin Deficiency: Genetic Reasons for Increasing Biotin
Biotin, also known as vitamin B7 or vitamin H, is a cofactor that aids in the metabolism of fats, carbohydrates, and proteins. Biotin deficiency due to diet is pretty rare, but there are genetic variants that can increase your risk for biotin deficiency or insufficiency.
Sulfotransferases: SULT Genes, Phase II Detoxification, and Sulfur
The SULT genes help with phase II detoxification of estrogens, neurotransmitters, certain carcinogens, and steroid hormones.
Melanopsin: Light response, Circadian Rhythm, and Blue Light Exposure
Melanopsin is the receptor for blue light. It is found in the retina, skin, adipose tissue, and blood vessels. Genetic variants can impact reaction to blue light.
Estrogen: How It Is Made and How We Get Rid of It
Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.
Chronic Inflammation: Causes and Natural Solutions
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Long Covid: Genetics Research, Root Causes, and Possible Solutions
Long Covid is the persistence of symptoms after having COVID-19. Learn more about the underlying causes and treatments backed by the newest research.
Plasmalogens: Healthy Brain Aging and More
Plasmalogen levels in the brain are key to brain health. Low plasmalogen is linked to Alzheimer’s and ME/CFS. Healthy ways to boost your levels.
Histamine, Mast Cell Activation, and Early Morning Insomnia
Histamine rising in the early morning hours may cause early waking insomnia. Mast cells and circadian rhythm disruption at the root.
Restless Leg Syndrome and Periodic Limb Movement Disorder (PLMD): Genes and Solutions
Many know the frustration of disrupted sleep due to RLS and periodic limb movement disorder (PLMD). Genes play a role in your risk for these disorders, and there are specific research-based treatments to explore.
Mitochondria Topic Summary
BookmarkThe Mitochondria Summary Report is a handy way to see which articles may be most relevant to you. These summaries are attempting to distill the complex information down into just a few words. Please see the linked articles for details and complete references. Please allow the page to fully load … Read more
Dopamine Receptor SNPs: Addiction, Mood, ADHD, and Schizophrenia
Dopamine is a powerful player in our cognitive function – impacting mood, movement, and motivation. Genetic variants in the dopamine receptors influence addiction, ADHD, neurological diseases, depression, psychosis, and aggression.
Lithium Orotate and Vitamin B12: Benefits for Mood and Cognitive Support
For some people, low-dose, supplemental lithium orotate is a game changer when combined with vitamin B12. But other people may have little to no response. The difference may be in your genes.
Wilson’s disease: ATP7B Gene Mutations and Copper Accumulation in the Brain
Mutations in ATP7B can cause copper dysregulation and Wilson’s disease. People carrying one copy of the mutation may also have subtle changes.
Saffron Extract: What does the research show?
Recent clinical trials show that saffron extract is as effective as standard medications in some people for ADHD, Alzheimer’s, major depressive disorder, and high cholesterol.
Plasminogen Activator Inhibitor-1 (PAI-1): Regulator of Clotting
Plasminogen Activator Inhibitor (PAI-1) is an important enzyme in the regulation of the breakdown of blood clots and fibrosis. Genetic variants impact the amount of PAI-1.
Chronic Lyme: Genetic Susceptibility
The interesting thing about Lyme disease is that the genetic variants you carry impact both how the disease affects you and how well antibiotics work for you. Learn whether your genetic variants are linked to post-treatment Lyme disease symptoms such as joint pain. (Member’s article)
Agmatine: Neuropathic pain and mood
Acting as a neurotransmitter and neuromodulator, agmatine holds promise for neuropathic pain, depression, and brain function.
Lion’s Mane: Cognitive function, nerve regeneration
Lion’s mane mushrooms have a long history of being used as a medicinal food for increasing energy, improving nerve function, and boosting brain power.
Multiple Chemical Sensitivity (MCS): Genetics, Causes, and Solutions
Struggling with Multiple Chemical Sensitivity (MCS)? Learn about the connection between genetics, detoxification enzymes, and the olfactory system.
COMT: How to Optimize Your Supplements for Your COMT Genotype
Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.