Melanopsin: Light response, circadian rhythm, and blue light exposure
Melanopsin is the receptor for blue light. It is found in the retina, skin, adipose tissue, and blood vessels. Genetic variants can impact reaction to blue light.
asthma
MRGPRX2: Mast Cells, Itching, & Drug Hypersensitivity Reactions, Including Fluoroquinolones
MRGPRX2 is a recently discovered mast cell receptor. It is linked to drug hypersensitivity reactions as well as asthma, rosacea, and IBD.
TNF-alpha: Inflammation, Chronic Diseases, and Genetic Susceptibility
Discover the role of TNF-alpha in inflammation and its link to chronic diseases. Learn how genetic variants affect TNF-alpha levels and explore natural solutions for chronic inflammation.
Estrogen, histamine, and mast cell connections
Mast cells can be more easily triggered in the presence of high estrogen or estrogen-mimicking compounds. Histamine can also trigger mast cell degranulation. Together, this can cause a lot of symptoms related to mast cell activation.
IL-13: Elevating Th2 Immune Response and Asthma risk
Interleukin-13 (IL-13) is a signaling molecule important in the immune response. Excessive IL-13 can tip you toward a Th2-dominant immune response, and variants increase the risk of allergies and asthma.