BPA

HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions

Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.

What is YOUR risk of heart disease?

Coronary artery disease (CAD) is heritable. Understanding your genes and a ‘heart healthy’ lifestyle can prevent heart attacks and death.

Glucuronidation: UGT genetic variants, phase II detoxification

The UGT family of enzymes is responsible for an important part of phase II detoxification. This article explains what the UGT enzymes do in the body, how your genes impact this part of detoxification, and lifestyle factors that can increase or decrease this detox process.

Genetic Causes of Male Infertility

Almost 10% of couples worldwide struggle with infertility. Learn more about your genetic susceptibility and dig deeper into the lifestyle factors that could affect your sperm.

Depression genes

Depression, genetics, and mitochondrial function

How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.

Thyroid Hormone Levels and Your Genes

The thyroid is a master regulator controlling many of your body’s systems. It is integral for metabolism and body temperature. Learn more about specific thyroid-related variants and check your genetic raw data.

PCOS: Genetics and Root Causes

Polycystic ovarian syndrome (PCOS) is an endocrine disorder causing an increase in androgen hormone production in women. It also increases the risk of infertility. PCOS affects 5 -10% of premenopausal women, and genetics plays a large role in whether you have PCOS.

Growing up ‘big boned’: MC4R gene and obesity

There are several key players in our body’s regulation of hunger, satiety, and energy expenditure. Leptin and ghrelin are two pivotal hormones involved in our desire to eat. Within that leptin pathway, another key regulator of our body weight is MC4R. (Member’s article)

Low testosterone and your genes

While diet and lifestyle play a role in testosterone levels, in males, there is a strong genetic component as well. Check out your genes to see if they are playing a role in your low T levels — and then check out the Lifehacks.

Genes that increase the risk of uterine fibroids

Uterine fibroids are a problem for a lot of women, especially after age 30. Fibroids are benign tumors that grow in the muscle cells of the uterus. This article will dig into the causes of fibroids, explain how your genetic variants can add to the susceptibility, and offer solutions that are backed by research. (Member’s article)

BPA: How Your Genes Influence BPA Detoxification

BPA, a chemical found in some plastics, has been linked to a variety of health issues in people. Learn more about BPA and the research into genetic responses to this chemical.

Estrogen: How it is made and how we get rid of it

Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.