Growing up ‘big boned’: MC4R gene and obesity

There are several key players in our body's regulation of hunger, satiety, and energy expenditure. Two pivotal hormones involved in our desire to eat are leptin and ghrelin. Within that leptin pathway, another key regulator of our body weight is MC4R.

This explanation is going to get a bit complicated, so for all of you impatient people:  Jump ahead to check your genes for MC4R variants.
Appetite, Weight Gain, MC4R gene:
The arcuate nucleus is a region within the hypothalamus in our brain. ...


 

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