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Mast cell activation syndrome genetics and solutions

Mast Cells: MCAS, Genetics, and Solutions

Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.

New research on FTO gene variants, FTO and heart disease, viral susceptibility

FTO and m6A Methylation

Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.

Lipoprotein a genetic variants, LP(a) heart attack risk, ways to lower LP(a)

Lipoprotein(a): Genetics and Lp(a) Levels

High Lp(a) levels are a big risk factor for sudden heart attacks. Your Lp(a) levels are mainly controlled by your genetic variants. Check to see if you carry genetic variants that increase or decrease Lp(a).

Genetic variants that cause Hemochromatosis, symptoms of Hemochromatosis

Building Up Iron: Hemochromatosis Mutations

A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.

Fibrinogen formation, genetic variants that affect fibrinogen levels, natural pathways to lower fibrinogen, heart disease and fibrinogen

Elevated Fibrinogen: Risk factor for blood clots

Fibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level.

Vitamin B6 deficiency genes, foods high in vitamin B6

Vitamin B6: Genetics, Absorption, and Deficiency

Vitamin B6 is an important co-factor in hundreds of different enzymatic reactions. Low levels of B6 are linked to an increased risk of diabetes, cardiovascular disease, neurodegenerative diseases, and cancer. B6 is also essential for reducing oxidative stress and inflammation.

HPA Axis disfunction, ways to reduce cortisol levels, genetic variants related to HPA Axis disfunction.

HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions

Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.

NLRP3 Inflammasome, Genetics, and Chronic Inflammation

NLRP3: Genetic Variants that Increase Chronic Inflammation

Explore NLRP3 inflammasome genetics: How variants drive chronic inflammation in Alzheimer’s, diabetes, and autoimmune diseases. Discover triggers, health risks, and lifehacks like zinc & vitamin D to modulate it.

LDL cholesterol genes, natural supplements to lower cholesterol

LDL Cholesterol: Genetics, Personalized Solutions

Your genes combine with your diet to influence your LDL cholesterol level. Learn more about why LDL cholesterol levels may matter in heart disease and find out how your genes are important here.

Blood Pressure, MTHFR, and Riboflavin

Blood Pressure, MTHFR, and Riboflavin

The common MTHFR C677T variant increases the relative risk of high blood pressure. Learn how to add more Riboflavin (B2) into your diet to reduce risk.

Estrogen, Histamine, and Mast Cell Connections, genetic variants that affect histamine and mast cells, genetic variants that affect estrogen receptors

Estrogen, Histamine, and Mast Cell Connections

Mast cells can be more easily triggered in the presence of high estrogen or estrogen-mimicking compounds. Histamine can also trigger mast cell degranulation. Together, this can cause a lot of symptoms related to mast cell activation.