Advanced Glycation End Products

Recent research shows that advanced glycation end products (AGEs) are a causative factor in many degenerative diseases – including almost all of the diseases associated with aging. AGEs have been linked to Alzheimer’s, heart disease, diabetes, chronic kidney disease, wrinkles and loss of skin…

Melatonin: Key to Health and Longevity

It seems like everything that I’ve written about lately has a common thread: melatonin. When I started weaving together all those melatonin threads, a big picture was revealed. You could say it is a… tapestry of health. Melatonin may actually be the key to…

Heart disease, cancer, diabetes: A gene that ties together the “Big 3”

When it comes to chronic diseases, the Big 3 are heart disease, cancer, and type 2 diabetes. Heart disease is the number one killer in the US, with cancer a close second. Diabetes numbers are increasing at an alarming rate. I recently was reading several…

Early to bed, early to rise – helps with weight loss and diabetes

Meal timing and light at night are modern issues that impact diabetes and obesity risk.

Genetics and Type 2 Diabetes

What comes to mind as far as the risk of type 2 diabetes? Usually first up is the mental picture of someone eating donuts and slurping down a Big Gulp.  While diet definitely contributes to diabetes risk, not everyone who eats donuts and slurps…

Are you at a higher risk for diabetes? Check your TCFL72 variants

Type-2 diabetes affects about 9% of the US population and millions of people worldwide. For the over 65 crowd, the statistics are even more startling: one in four has type-2 diabetes. While the overall numbers are scary, it is interesting to note that the…

Diet – Gene Interaction in Type 2 Diabetes Risk

A new study just came out in the FASEB Journal that looked at the interaction between polyunsaturated fat and the Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-α (PPARGC1A) gene.  The study found that those with the minor allele (C) of rs4235308 combined with a lower PUFA (polyunsaturated…

Building Up Iron: Check your genes to see how iron affects your health

Hemochromatosis is a fairly common genetic disease that causes iron to build up in the body. Knowing that you carry the genetic variants for hemochromatosis can literally add years to your life since you can prevent the buildup of iron through giving blood. This…

PPARG: A genetic variant that can protect against obesity and type-2 diabetes, but only if you eat the right diet.

The PPARG (peroxisome proliferator-activated receptor gamma) gene has been associated with obesity, metabolic syndrome, and risk for type-2 diabetes. This gene is involved in the regulation of fatty acid storage and in glucose metabolism. PPAR-gamma is activated by omega-6 polyunsaturated fatty acids and regulates…

Diabetes and your genes – TCF7L2 snp

There’s a new study out  on the connection between the TCF7L2 gene, diet, and diabetes. I think it is important if you have type 2 diabetes, or if it runs in your family, to understand where YOUR genetic susceptibility lies. There are several different…